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TranscriptomicsTranscription profiling of human immature dendritic cells treated with Lipopolysaccharide (LPS) vs Taxol (paclitaxel)
Generation of monocyte-derived dendritic cells (DC). Immature DC were prepared from peripheral blood mononuclear cells (PBMCs) isolated from whole blood of healthy donors. A minimum of 3 individual donor blood was used for each experiment. PBMCs were incubated with anti-CD14 microbeads (Miltenyi Bio...
ORGANISM(S): Homo sapiens 
2009-11-27 | E-MEXP-2465 | biostudies-arrayexpress
MetabolomicsMetabolomics revealed the influence of breast cancer on lymphatic endothelial cell metabolism, metabolic crosstalk, and lymphangiogenic signaling in co-culture

Breast cancer metastasis occurs via blood and lymphatic vessels. Breast cancer cells 'educate' lymphatic endothelial cells (LECs) to support tumor vascularization and growth. However, despite known metabolic alterations in breast cancer, it remains unclear how lymphatic endothelial cell metabolis...

2024-06-25 | MTBLS859 | MetaboLights
UnknownAssociations Between Capillary Diameter, Capillary Density, and Microaneurysms in Diabetic Retinopathy: A High-Resolution Confocal Microscopy Study.
Not available
S-EPMC7873504 | biostudies-literature
ProteomicsLC-MSMS of Hela cell extracts on pull down with de novo modular peptide binding proteins
we describe a general approach for de novo design of proteins made out of repeating units that bind peptides with repeating sequences such that there is a one to one correspondence between repeat units on the protein and peptide. We develop a rapid docking plus geometric hashing method to identify p...
ORGANISM(S): Homo sapiens (Human) 
2023-03-17 | PXD038492 | Pride
Hela Gelbands Lc-msms 
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
TranscriptomicsA compendium of myeloma associated chromosomal copy number abnormalities and their prognostic value
To obtain a comprehensive genomic profile of presenting multiple myeloma cases we performed high resolution single nucleotide polymorphism (SNP) mapping array analysis in 114 samples alongside 258 samples analysed by U133 Plus 2.0 expression array (Affymetrix). We examined DNA copy number alteratio...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-21349 | biostudies-arrayexpress
TranscriptomicsHigh Myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas
In this study we investigated to which extend aberrant c Myc activity plays a functional role in other aNHL and whether it is independent from MYC translocations. Based on a combined microarray analysis of human germinal centre (GC) B cells transfected with c Myc and 220 aNHLs cases, we developed a ...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-31311 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA sequencing of putative AIRE+ dendritic cells from human paediatric tonsillitis
Characterisation and identification of putative human extra-thymic AIRE-expressing cells from paediatric tonsillitis samples using single -cell transcriptome profiling.
ORGANISM(S): Homo sapiens 
2019-01-14 | E-MTAB-7381 | biostudies-arrayexpress
TranscriptomicsDeciphering the molecular immune response to COVID-19 using single cell multi-omics
Multi-omics single-cell profiling of surface proteins, gene expression and lymphocyte immune receptors from hospitalised COVID-19 patient peripheral blood immune cells and healthy controls donors. Identification of the coordinated immune cell compositional and state changes in response to SARS-CoV-2...
ORGANISM(S): Homo sapiens 
2021-03-17 | E-MTAB-10026 | biostudies-arrayexpress
UnknownT1DMicro: A Clinical Risk Calculator for Type 1 Diabetes Related Microvascular Complications.
Not available
S-EPMC8583376 | biostudies-literature
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