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MetabolomicsMetabolomic Microbiome Modulations Induced by ZIF8@ZIF67 Supplementation in the Midgut of Bombyx mori
Bombyx mori is an economically crucial lepidopteran insect, and its health is closely related to the gut microbiota and metabolic status. Our previous research confirmed that metal organic frameworks nanocomposite ZIF8@ZIF67 supplementation can significantly enhance silkworm survival rates upon bact...
2025-05-28 | MTBLS12521 | MetaboLights
MetabolomicsImaginal disc growth factor maintains cuticle structure and controls melanization in the spot pattern formation of Bombyx mori

The complex stripes and patterns of insects play key roles in behavior and ecology. However, the fine-scale regulation mechanisms underlying pigment formation and morphological divergence remain largely unelucidated. Here we demonstrated that imaginal disc growth factor (IDGF) maintains cuticle s...

2020-09-20 | MTBLS1825 | MetaboLights
MetabolomicsDetoxification metabolic adaptation of Bombyx mori to artificial diet and functional study of key detoxification gene BmGSTd2

The exceptional adaptability of insects to diverse food sources is central to their survival and evolutionary success. However, the molecular mechanisms underlying this rapid adaptation remain largely uncharacterized. In this study, adaptive phenotypic, transcriptomic, and metabolomic differences...

2026-01-27 | MTBLS13782 | MetaboLights
TranscriptomicsMicroRNAs of Bombyx mori identified by Solexa sequencing
Background: MicroRNA (miRNA) and other small regulatory RNAs contribute to the modulation of a large number of cellular processes. We sequenced three total RNA libraries prepared from the whole body, and the anterior and posterior silk glands of Bombyx mori, with a view to expanding the repertoire o...
ORGANISM(S): Bombyx mori 
2010-02-01 | E-GEOD-17965 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling during the life cycle of the silkworm (Bombyx mori)
Background: MicroRNAs (miRNAs) are expressed by a wide range of eukaryotic organisms, and function in diverse biological processes. Numerous miRNAs have been identified in Bombyx mori, but the temporal expression profiles of miRNAs corresponding to each stage transition over the entire life cycle of...
ORGANISM(S): Bombyx mori 
2010-02-20 | E-GEOD-18030 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of the fifth-instar posterior silk gland of Bombyx mori
Background: The growth and development of the posterior silk gland and the biosynthesis of the silk core protein at the fifth larval instar stage of Bombyx mori are of paramount importance for silk production. Results: Here, aided by next-generation sequencing and microarry assay, we profile 1,229 m...
ORGANISM(S): Bombyx mori 
2014-07-30 | E-GEOD-56380 | biostudies-arrayexpress
TranscriptomicsMicroRNAs show diverse and dynamic expression patterns in multiple tissues of Bombyx mori
Background: MicroRNAs (miRNAs) repress target genes at the post-transcriptional level, and function in the development and cell-lineage pathways of host species. Tissue-specific expression of miRNAs is highly relevant to their physiological roles in the corresponding tissues. However, to date, few m...
ORGANISM(S): Bombyx mori 
2010-02-20 | E-GEOD-18039 | biostudies-arrayexpress
ProteomicsProteomic analysis of Bombyx mori prothoracic glands from day 0 and day 6 of the 5th instar
The project aim was to identify the proteins expressed by the prothoracic gland cells during the final larval stage of the model insect, Bombyx mori.
ORGANISM(S): Bombyx mori (Silk moth) 
2016-06-08 | PXD004265 | Pride
Prothoracic glands Proteomic analysis Bombyx mori Ecdysteroid 
TranscriptomicsExpression of 50-500nt ncRNAs in silkworm Bombyx mori during two developmental transitions
We have performed the first systematic identification and analysis of intermediate size ncRNAs (50-500 nt) in the silkworm genome. We identified 194 novel ncRNAs, the expression profiles of them during the transitions from the egg to the first instar larva and from the fifth instar larva to the pupa...
ORGANISM(S): Bombyx mori 
2010-12-22 | E-GEOD-22912 | biostudies-arrayexpress
TranscriptomicsGenome-wide Identification of Polycomb Target Genes Reveals a Functional Association of Pho with Scm in Bombyx mori
Polycomb group (PcG) proteins are involved in chromatin modifications for maintaining gene repression that play important roles in the regulation of gene expression, tumorigenesis, chromosome X-inactivation, and genomic imprinting in Drosophila melanogaster, mammals, and even plants. PcG proteins ac...
ORGANISM(S): Bombyx mori 
2012-04-17 | E-GEOD-34246 | biostudies-arrayexpress
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