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ProteomicsInvestigation of signalling pathways and potential mechanisms of drug resistance associated with the two transmissible cancers in the Tasmanian devil using phosphoproteomics
Investigation of signalling pathways and potential mechanisms of drug resistance associated with the two transmissible cancers in the Tasmanian devil using phosphoproteomics Two transmissible cancers, Devil Facial Tumor 1 (DFT1) and Devil Facial Tumor 2 (DFT2), have caused significant declines in Ta...
ORGANISM(S): Sarcophilus harrisii 
2026-03-09 | PXD058352 | Pride
Kinase inhibitor resistance Receptor tyrosine kinase inhibition Tasmanian devils Transmissible cancer Xenograft Devil facial tumour disease Phosphoproteomics Pdgfr Erbb 
TranscriptomicsHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Impairment of hepatic growth hormone (GH)- janus kinase (JAK) 2- signal transducer and activator of transcription (STAT) 5 signaling is associated with non-alcoholic fatty liver disease, while persistently high levels of GH can result in hepatic inflammation and liver cancer. Despite its anti-steato...
ORGANISM(S): Mus musculus 
2016-10-01 | E-MTAB-3774 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 3 genotypes in mouse
For transcription profiling six mouse T cells samples were analyzed: 3 genotypes 2 samples for each genotype were complared. Two wt animals-control;2 animals containing deficiency allele (Df11(1)) on chromosome 11 and 2 with the reciprocal duplication on chromosome 11(Dp11(1)). The part of the chrom...
ORGANISM(S): Mus.Musculus 
2011-11-01 | E-MTAB-447 | biostudies-arrayexpress
UnknownBlocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma
Not available
S-SCDT-10_15252-EMMM_202115200 | biostudies-other
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