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MetabolomicsUntargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma
Neuroblastoma (NB) is the most common extracranial malignant tumor in children. Although the survival rate of NB has improved over the years, the outcome of NB still remains poor for over 30% of cases. A more accurate risk stratification remains a key point in the study of NB and the availability of...
2023-07-14 | MTBLS4294 | MetaboLights
ProteomicsPlasma-derived exosome proteins as novel diagnostic and prognostic biomarkers in neuroblastoma patients
Neuroblastoma (NB) is the most common extracranial solid tumor during infancy, causing up to 10% of mortality in children. NB shows notable heterogeneity with regard to histology and clinical behavior, ranging from low-risk localized tumors (LR-NB) to high-risk disease (HR-NB), characterized by aggr...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD042422 | Pride
Exosomes Proteomics Mass spectrometry Extracellular vesicles Neuroblastoma 
ProteomicsMembrane IL-18 Identifies a Unique Human Macrophage Subset with Distinct Phenotypic and Functional Properties
This study adds a tile to the macrophage heterogeneity in humans. We characterize a unique macrophage population expressing membrane-associated IL-18 (mIL-18) that shows peculiar proteomic, phenotypic, ultrastructural, and functional properties. mIL-18+ macrophages exhibit increased levels of key pr...
ORGANISM(S): Homo sapiens (Human) 
2025-11-17 | PXD058726 | Pride
Il-18 Macrophages Adult cancer patients  pediatric neuroblastoma Endocytosis Trem2 
UnknownShort- and mid-term multidisciplinary outcomes of newborns exposed to SARS-CoV-2 in utero or during the perinatal period: preliminary findings.
Not available
S-EPMC8747884 | biostudies-literature
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