Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of mouse striatum treated with morphine, animals from four inbred strains
Chronic opiate use produces molecular and cellular adaptations in the nervous system, leading to tolerance, physical dependence and addiction. Genome-wide comparison of morphine-induced changes in brain transcription of mouse strains with different opioid-related phenotypes provides an opportunity t...
ORGANISM(S): Mus musculus 
2009-02-07 | E-GEOD-7762 | biostudies-arrayexpress
TranscriptomicsWhole-genome expression profile in zebrafish embryos after chronic exposure to morphine
A great number of studies have investigated changes induced by morphine exposure in gene expression using several experimental models. In this study, we examined gene expression changes during chronic exposure to morphine during maturation and differentiation of zebrafish CNS. Our study identified d...
ORGANISM(S): Danio rerio 
2014-09-04 | E-GEOD-61062 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression and opioid signaling
To study the relationship between microRNAs and μ-opioid receptor (MOR) signaling, we examined microRNA expression after chronic morphine or fentanyl treatment in rat primary hippocampal neurons and in mouse hippocampus. Mouse cerebellum region was also tested as a negative control to eliminate mic...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-14268 | biostudies-arrayexpress
ProteomicsLiver and kidney under opioid exposure, DIA data
In the presented investigations we performed a quantitative proteomic analysis of rat liver and kidney tissues following exposure to morphine (10 mg/kg, once daily, for 10 days, intraperitoneally), compared to untreated controls. Although opioids are generally considered safe for both organs during ...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-01-26 | PXD068084 | Pride
Liver Kidney Morphine influence Dia data 
UnknownInfluence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide.
Not available
S-EPMC5694499 | biostudies-literature
UnknownOCT1 genetic variants influence the pharmacokinetics of morphine in children.
Not available
S-EPMC4116670 | biostudies-literature
UnknownABCC3 and OCT1 genotypes influence pharmacokinetics of morphine in children.
Not available
S-EPMC4190075 | biostudies-literature
UnknownNo significant influence of OCT1 genotypes on the pharmacokinetics of morphine in adult surgical patients.
Not available
S-EPMC9298338 | biostudies-literature
UnknownUnconditioned and learned morphine tolerance influence hippocampal-dependent short-term memory and the subjacent expression of GABA-A receptor alpha subunits.
Not available
S-EPMC8428970 | biostudies-literature
UnknownInfluence of Intravenous S-Ketamine on the Pharmacokinetics of Oral Morphine in Healthy Volunteers.
Not available
S-EPMC10852043 | biostudies-literature
Sort   by:  
 Page size