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ProteomicsA 6-Month Systems Toxicology Inhalation/Cessation Study in ApoE-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of the Modified-Risk Tobacco Products CHTP1.2 and THS2.2 Compared with the Effects of Conventional Cigarettes [Lung iTRAQ data].
Cigarette smoke (CS) causes adverse health effects that may occur shortly after smoking initiation and lead to the development of respiratory disease (chronic obstructive pulmonary disease), cardiovascular disease, and cancer. To reduce the risk of smokers developing smoking-related diseases, Philip...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-18 | PXD010875 | Pride
Mouse Lung Systems toxicology Itraq Lc-ms/ms 
ProteomicsA 6-Month Systems Toxicology Inhalation/Cessation Study in ApoE-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of the Modified-Risk Tobacco Products CHTP1.2 and THS2.2 Compared with the Effects of Conventional Cigarettes [Liver iTRAQ data].
Cigarette smoke (CS) causes adverse health effects that may occur shortly after smoking initiation and lead to the development of respiratory disease (chronic obstructive pulmonary disease), cardiovascular disease, and cancer. To reduce the risk of smokers developing smoking-related diseases, Philip...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-23 | PXD010874 | Pride
Mouse Systems toxicology Liver Itraq Lc-ms/ms 
ProteomicsA 6-Month Systems Toxicology Inhalation/Cessation Study in ApoE-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of the Modified-Risk Tobacco Products CHTP1.2 and THS2.2 Compared with the Effects of Conventional Cigarettes [Heart iTRAQ data].
Cigarette smoke (CS) causes adverse health effects that may occur shortly after smoking initiation and lead to the development of respiratory disease (chronic obstructive pulmonary disease), cardiovascular disease, and cancer. To reduce the risk of smokers developing smoking-related diseases, Philip...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-23 | PXD010873 | Pride
Mouse Heart Systems toxicology Itraq Lc-ms/ms 
ProteomicsSystems toxicology assessment of CHTP1.2 [Liver Data]
Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a potential MRTP that uses a pressed carbon heat source to generate an aerosol by heating tobacco. This study reports the results from the systems toxi...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-03-19 | PXD008423 | Pride
Rat Mrtp Itraq Lc-msms Systems toxicology 
ProteomicsSystems toxicology assessment of CHTP1.2 [RNE Data]
Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a potential MRTP that uses a pressed carbon heat source to generate an aerosol by heating tobacco. This study reports the results from the systems toxi...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-03-19 | PXD008424 | Pride
Rat Mrtp Itraq Lc-msms Systems toxicology 
ProteomicsSystems toxicology assessment of CHTP1.2 [Lung Data]
Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a potential MRTP that uses a pressed carbon heat source to generate an aerosol by heating tobacco. This study reports the results from the systems toxi...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-03-19 | PXD008422 | Pride
Rat Mrtp Itraq Lc-msms Systems toxicology 
ProteomicsRespiratory effects of exposure to aerosol from the candidate modified-risk tobacco product THS 2.2 in an 18-month systems toxicology study with A/J mice [Lung data]
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-13 | PXD016460 | Pride
Lc-msms Mouse Lung Systems toxicology Itraq 
ProteomicsRespiratory effects of exposure to aerosol from the candidate modified-risk tobacco product THS 2.2 in an 18-month systems toxicology study with A/J mice [RNE data]
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-13 | PXD016466 | Pride
Lc-msms Respiratory nasal epithelium Mouse Systems toxicology Itraq 
MetabolomicsComparative metabolomics of Mycoplasma bovis and Mycoplasma gallisepticum reveals fundamental differences in active metabolic pathways and suggests novel gene annotations
Mycoplasmas are simple, but successful parasites that have the smallest genome of any free-living cell and are thought to have a highly streamlined cellular metabolism. Here we have undertaken a detailed metabolomic analysis of two species, Mycoplasma bovis and Mycoplasma gallisepticum, which cause ...
2017-10-10 | MTBLS535 | MetaboLights
UnknownAutomated Competitive Protein-Binding Assay for Total 25-OH Vitamin D, Multicenter Evaluation and Practical Performance.
Not available
S-EPMC6807057 | biostudies-literature
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