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To identify the putative salivary tPA activator, we fractionated salivary proteins by size-exclusion chromatography and identified fraction Z8 as the strongest tPA activator, whereas the adjacent fractions Z7 and Z9 activated tPA at lower levels. Mass spectrometry analysis of these fractions identif...
ORGANISM(S): Anopheles gambiae (African malaria mosquito) 
2025-01-16 | PXD052155 | Pride
Background: Anopheles culicifacies is a rural vector of malaria in tropical and sub tropical South East Asian region. The salivary gland of the mosquito is the target for sporozoite interaction, blood feeding behavior, haemostasis and vector-parasite interactions. Malaria parasite matures inside th...
ORGANISM(S): Anopheles culicifacies A 
2016-09-13 | PXD003450 | Pride
Plasmodium sporozoites, the stage that initiates a malaria infection, must invade the mosquito salivary glands before transmitting to a vertebrate host. However, the effects of sporozoite invasion on salivary gland physiology and saliva composition remain largely unexplored. We examined the impact o...
ORGANISM(S): Anopheles gambiae str. PEST Plasmodium berghei ANKA 
2025-12-01 | PXD057628 | Pride
Salivary gland proteins of Anopheles mosquitoes offer attractive targets to understand interactions with sporozoites, blood feeding behavior, homeostasis and immunological evaluation of malaria vectors and parasite interactions. To date limited studies have been carried out to elucidate salivary pro...
ORGANISM(S): Anopheles stephensi (Asian malaria mosquito) 
2015-01-08 | PXD001647 | Pride
Although the salivary transcriptome of adult mosquitoes has been thoroughly described in several recent papers, very little information exists regarding the biological role of larval salivary glands in the Culicidae. We used whole-transcriptome Affymetrix® chips to compare the transcriptional profi...
ORGANISM(S): Anopheles gambiae 
Plasmodium sporozoites, the stage that initiates a malaria infection, must invade the mosquito salivary glands before transmitting to a vertebrate host. However, the effects of sporozoite invasion on salivary gland physiology and saliva composition remain largely unexplored. We examined the impact o...
ORGANISM(S): Anopheles gambiae str. PEST Plasmodium berghei ANKA Plasmodium falciparum NF54 
2026-07-06 | PXD057587 | Pride
Dengue viruses (DENV) are generally maintained in a cycle which requires horizontal transmission via their arthropod vector, Ae. Aegypti, to the vertebrate host. One important consequence of this process is the interference of these arboviruses with both invertebrate and vertebrate immune systems. W...
ORGANISM(S): Aedes aegypti 
Plasmodium sporozoites, the stage that initiates a malaria infection, must invade the mosquito salivary glands before transmitting to a vertebrate host. However, the effects of sporozoite invasion on salivary gland physiology and saliva composition remain largely unexplored. We examined the impact o...
ORGANISM(S): Anopheles gambiae str. PEST Plasmodium berghei ANKA 
2025-12-01 | PXD057585 | Pride
Aedes aegypti is a major vector for dengue, chikungunya and yellow fever. Though salivary gland plays a crucial role in transmission of virus and vector life cycle, there is no global and unbiased published report on salivary gland proteome of Ae. aegypti. In this study, we have carried out mass spe...
ORGANISM(S): Aedes aegypti aegypti 
2017-02-28 | PXD002468 | Pride
Many eukaryotic developmental and cell fate decisions are effected post-transcriptionally that mechanistically involve RNA binding proteins as regulators of translation of key mRNAs. In the unicellular eukaryote malaria parasite, Plasmodium, one of the most dramatic changes in cell morphology and fu...
ORGANISM(S): Plasmodium berghei 
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