Mouse brain proteomics

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Proteomics (2087)
Unknown (660)
Genomics (63)
Transcriptomics (47)
Other (13)
Metabolomics (11)
Models (2)
Methylation profiling (2)
Multiomics (1)

Organisms

Schizosaccharomyces pombe (1605)
Sinorhizobium meliloti BL225C (1605)
Sus scrofa domesticus (1605)
Saccharomyces cerevisiae (1605)
Staphylococcus aureus (1605)
Rattus norvegicus (1605)
Escherichia coli (1605)
Homo sapiens (1605)
Shigella flexneri (1605)
Allexis (1605)
Shigella (1605)
Mus musculus (221)
Homo sapiens (61)
Halobacterium salinarum NRC-1 (10)
cellular organisms (4)
Saccharomyces cerevisiae (2)
Mus (2)
Rattus norvegicus (2)
Bos taurus (2)
Peromyscus leucopus (1)
Streptococcus suis SC070731 (1)
Human CSF-associated densovirus (1)
artificial sequences (1)
Sus scrofa domesticus (1)
Rattus rattus (1)
Arabidopsis thaliana (1)
Escherichia coli (1)
Acinetobacter baumannii (1)
Fusarium sinicum (1)
Oncorhynchus mykiss (1)

Organisms

Mus musculus (37)
Homo sapiens (14)

Repository

pride (1605)
MassIVE (240)
iProX (105)
jPOST (86)
ENA (56)
geo (42)
biostudies-arrayexpress (29)
PeptideAtlas (22)
PanoramaPublic (11)
MetaboLights (10)
GPMDB (8)
PAXDB (7)
BioModels (2)
GNPS (1)
NODE (1)

Tissue

Brain (1264)
Cell culture (155)
Liver (101)
Kidney (74)
Heart (65)
Lung (46)
Spleen (35)
Microglial cell (33)
Neuron (30)
Cerebrospinal fluid (28)
Blood plasma (27)
Permanent cell line cell (23)
Hippocampus (22)
Fibroblast (22)
Epithelial cell (21)
Macrophage (18)
Skeletal muscle (17)
Astrocyte (16)
Testis (15)
Cerebral cortex (14)
Primary cell (13)
Colon (13)
Oligodendrocyte (11)
Muscle (11)
Blood serum (11)
Hippocampal neuron (11)
Blood (11)
Endothelial cell (10)
Brain (1)
Others (1)

Disease

Alzheimer's disease (100)
Parkinson's disease (41)
Disease free (35)
Huntington Disease (28)
Brain cancer (27)
Amyotrophic lateral sclerosis (17)
Autism spectrum disorder (13)
Brain glioblastoma multiforme (11)
Glioblastoma (9)
Not Available (8)
Multiple sclerosis (8)
Neuroblastoma (8)
Cardiovascular system disease (7)
Stroke (5)
Brain disease (5)
Neurodegenerative disease (5)
Fragile X syndrome (5)
Type 2 diabetes mellitus (5)
Breast cancer (5)
Wounds and Injuries (5)
Brain small vessel disease (4)
Alzheimer's disease 1 (4)
Frontotemporal dementia (4)
Brain ischemia (4)
Epilepsy (4)
Cerebrovascular disease (3)
Amyotrophic lateral sclerosis type 1 (3)
Prion disease (3)
Niemann-Pick disease (3)
Leigh disease (3)

Technology Type

Mass Spectrometry (1605)
Shotgun proteomics (834)
Bottom-up proteomics (354)
Data-dependent acquisition (173)
Affinity purification coupled with mass spectrometry proteomics (159)
Data-independent acquisition (131)
Gel-based experiment (90)
SWATH MS (77)
Top-down proteomics (54)
HDMSE (22)
SRM/MRM (17)
Chemical cross-linking coupled with mass spectrometry proteomics (13)
Mass spectrometry imaging (12)
Mass spectrometry (9)
MSE (9)
All-ion fragmentation (7)
DiaPASEF (4)
Proteogenomics (3)
Glycoproteomics (3)
Affinity proteomics (2)
Immunopeptidomics (2)
NMR spectroscopy (1)
PAcIFIC (1)

Instrument Platform

Orbitrap Fusion Lumos (49)
Orbitrap Fusion (30)
Orbitrap Exploris 480 (29)
Q Exactive (27)
Q Exactive HF (15)
LTQ Orbitrap Velos (15)
LTQ Orbitrap Elite (12)
Q Exactive HF-X (11)
Orbitrap Eclipse (9)
Instrument (8)
Q Exactive Plus (7)
LTQ (6)
TripleTOF 6600 (5)
LTQ Velos (4)
LTQ Orbitrap (4)
Agilent 6550 QTOF (3)
6495C Triple Quadrupole LC/MS (3)
TimsTOF fleX (3)
Orbitrap Astral (3)
Thermo QExactive HF (2)
NanoACQUITY UPLC System with 1D Technology (2)
Orbitrap Fusion ETD (2)
TimsTOF Pro (2)
Illumina HiSeq 2500 (1)
Illumina HiSeq 4000 (1)
NextSeq 500 (1)
Thermo Q-Exactive HF (QE) Quadrupole-Obitrap mass spectrometer (1)
Q-Exactive HF (QE) Quadrupole-Obitrap mass spectrometer (1)
Q-exactive (1)
MALDI Synapt G2-S HDMS (1)

Publication Date

2025 (343)
2024 (265)
2023 (262)
2026 (242)
2022 (237)
2021 (188)
2020 (134)
2019 (112)
2018 (94)
2017 (71)
2016 (55)
2015 (26)
2014 (24)
2006 (19)
2012 (9)
2008 (4)
2013 (4)
2010 (3)
2007 (3)
2009 (2)
2011 (2)

UNIPROT ID/AC

RL18A_MOUSE (7)
TPP1_MOUSE (7)
RL12_MOUSE (7)
TOP2B_MOUSE (7)
CDC5L_MOUSE (7)
WDR1_MOUSE (7)
MYH9_MOUSE (7)
MANF_MOUSE (7)
UB2L3_MOUSE (7)
CAP1_MOUSE (7)
HNRPQ_MOUSE (7)
KTN1_MOUSE (7)
COPB2_MOUSE (7)
ECI1_MOUSE (7)
CYBP_MOUSE (7)
RS23_MOUSE (7)
LGUL_MOUSE (7)
GDIB_MOUSE (7)
GSTO1_MOUSE (7)
TKT_MOUSE (7)
AT1A1_MOUSE (7)
IPYR_MOUSE (7)
PA2G4_MOUSE (7)
PPM1F_MOUSE (7)
HNRPK_MOUSE (7)
SET_MOUSE (7)
OAT_MOUSE (7)
RS4X_MOUSE (7)
ELAV1_MOUSE (7)
CALR_MOUSE (7)

ENSEMBL ID

ENSMUSP00000141097 (9)
ENSMUSG00000072849 (5)
ENSMUSG00000098557 (3)
ENSG00000170477 (2)
ENSMUSG00000032652 (1)
ENSMUSG00000094194 (1)
ENSMUSG00000076668 (1)
ENSMUSG00000076562 (1)
ENSMUSG00000076514 (1)
ENSMUSG00000090272 (1)
ENSMUSG00000103290 (1)
ENSMUSG00000096326 (1)
ENSMUSG00000095753 (1)
ENSMUSG00000095416 (1)
ENSMUSG00000094689 (1)
ENSMUSG00000094509 (1)
ENSMUSG00000094502 (1)
ENSMUSG00000094356 (1)
ENSMUSG00000093894 (1)
ENSMUSG00000076532 (1)
ENSMUSG00000098814 (1)
ENSMUSG00000096833 (1)
ENSMUSG00000094652 (1)
ENSMUSG00000094546 (1)
ENSMUSG00000076695 (1)
ENSMUSP00000141637 (1)
ENSMUSG00000095442 (1)
ENSMUSG00000094797 (1)
ENSMUSG00000094075 (1)
ENSMUSG00000093896 (1)

CHEBI ID

CHEBI:7274 (2)
CHEBI:16675 (2)
CHEBI:17364 (2)
CHEBI:17123 (2)
CHEBI:28541 (2)
CHEBI:30794 (2)
CHEBI:28888 (2)
CHEBI:44074 (2)
CHEBI:48714 (2)
CHEBI:28453 (2)
CHEBI:17425 (2)
CHEBI:16978 (2)
CHEBI:17173 (2)
CHEBI:16313 (2)
CHEBI:52595 (2)
CHEBI:16176 (2)
CHEBI:15816 (2)
CHEBI:2504 (2)
CHEBI:27468 (2)
CHEBI:28116 (2)
CHEBI:60210 (2)
CHEBI:8408 (2)
CHEBI:17703 (2)
CHEBI:16304 (2)
CHEBI:15982 (2)
CHEBI:15355 (2)
CHEBI:49268 (2)
CHEBI:28952 (2)
CHEBI:28424 (2)
CHEBI:18431 (2)

Metabolite Name

Ergothioneine (3)
Pipecolic acid (3)
Hypoxanthine (3)
Creatinine (3)
Xanthine (3)
Inosine (3)
Uridine (3)
PIP(16:0/22:2(13Z,16Z)) (2)
PGP(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) (2)
PGP(18:0/20:3(5Z,8Z,11Z)) (2)
PGP(18:0/22:4(7Z,10Z,13Z,16Z)) (2)
PC(22:5(4Z,7Z,10Z,13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) (2)
PC(MonoMe(11,3)/MonoMe(13,5)) (2)
PC(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) (2)
Azaspiracid 2 (2)
Diadenosine tetraphosphate (2)
(+)-2,3-Dihydro-3-methyl-1H-pyrrole (2)
PE(20:5(5Z,8Z,11Z,14Z,17Z)/22:2(13Z,16Z)) (2)
PC(14:0/22:0) (2)
PS(18:4(6Z,9Z,12Z,15Z)/20:5(5Z,8Z,11Z,14Z,17Z)) (2)
PG(16:0/22:5(7Z,10Z,13Z,16Z,19Z)) (2)
Asparagoside C (2)
PC(16:1(9Z)/18:4(6Z,9Z,12Z,15Z)) (2)
PG(16:0/18:1(11Z)) (2)
Ternatin (2)
PS(15:0/16:0) (2)
DG(20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (2)
Cyclopassifloside II (2)
PE(14:1(9Z)/14:1(9Z)) (2)
Avenestergenin A1 (2)

First Public Date

2026 (11)
2024 (10)
2025 (8)
2020 (7)
2022 (6)
2023 (4)
2021 (4)
2019 (3)
2014 (2)
2018 (1)

Lab affiliation

DZNE Munich, Neuroproteomics, Feodor-Lynen Str. 17, 81377 Munich, Germany (14)
Keck MS & Proteomics Resource Yale School of Medicine (8)
Neuroproteomics Group Department of Molecular Neurobiology Max Planck Institute for Multidisciplinary Sciences Hermann-Rein-Str. 3 37075 Goettingen Germany (7)
St Jude Children's Research Hospital (7)
Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA (6)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (6)
Head of the Curie Institute Mass Spectrometry Platform (6)
Research Unit for Molecular Medicine, Department of clinical Medicine, Aarhus University, Aarhus, Denmark (5)
EDyP (5)
IRCCS Istituto G Gaslini (5)
St. Jude Children's Research Hospital (5)
IBS, KAIST (4)
University of Alabama at Birmingham, O'Neal Mass Spectrometry Proteomics Shared Facility (4)
Institute of Neuronal Cell Biology Technical University of Munich Germany (4)
Ottawa Institute of Systems Biology and Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada (4)
Cleveland Clinic Lerner Research Institute Cardiovascular and Metabolic Sciences (4)
Max Planck Institute of Biochemistry (4)
Department of Biomolecular Sciences, Weizmann institute of Science, Israel (3)
Department of Immunobiology, College of Life Science and Technology, Jinan University, Guangzhou, China. (3)
State Key Laboratory of Reproductive Medicine (3)
Department of Neurology, Yale School of Medicine, Yale University, new haven CT, USA (3)
Research Institute for Microbial Diseases, Osaka University (3)
Institute of Physiology II, Universität Freiburg, Germany (3)
Ruhr-Universität Bochum, Medizinisches Proteom-Center (3)
Sequence database group (3)
First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (3)
Imperial College, Medicine, Level 3 Sherfield Building, Exhibition Road, SW7 2AZ London (3)
The Drug Discovery Lab, Mary S. Easton Center for Alzheimer’s Disease Research, Department of Neurology, David Geffen School of Medicine, 710 Westwood Plaza, University of California Los Angeles, Los Angeles, CA 90095, USA (3)
Tufts University (3)
Christoph Schaab (3)

IsPrivate

False (2)

Model Flag

Non Kinetic (2)

Modification

4-tetrahydrothiazine-3-carboxylic acid (7)
Not available (5)
15.994915 (3)
N6 (3)
57.021464 (3)
79.966331 (2)
-17.026549 (2)
42.010565 (2)
N6-dimethyl-L-lysine (2)
42.04695 (1)
229.162932 (1)
28.0313 (1)
Heavy form - site K (1)
Heavy form (1)
Medium form - site K (1)
Medium form - site N-term (1)
144.102062 (1)
0.984016 (1)
-18.010565 (1)
2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (12)
Proteomic profiling by array (10)
RNA-seq of coding RNA (4)
Cell line - Single-cell sequencing (1)
Comparative genomic hybridization by array (1)
RNA-seq of total RNA (1)

Release Date

2025 (90)
2023 (85)
2024 (75)
2022 (70)
2021 (69)
2020 (48)
2018 (42)
2019 (39)
2017 (27)
2015 (26)
2014 (26)
2016 (25)
2026 (14)
2012 (12)
2010 (11)
2013 (7)
2011 (6)
2008 (5)
2007 (5)
2009 (3)
2004 (2)
2006 (1)
2002 (1)

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Monocolonization with Bacteroides thetaiotaomicron exerts region-specific effects on Alzheimer’s disease-related traits in the murine brain

Bacteroides thetaiotaomicron (B. theta) dominates the gut microbiome of most mammals. This strictly anaerobic gut symbiont colonizes the mucus layer of host intestinal epithelial cells in both healthy and diseased conditions. Reduced neuronal and vagal afferent innervation observed in ge...

2025-12-15 | MTBLS12896 | MetaboLights

Ten Mouse Organs Proteome and Metabolome Atlas from Adult to Aging

The complexity of the aging process, encompassing numerous organs and systems, poses a significant challenge in identifying and targeting key factors that drive age-related decline. The multi-organ synchronous molecular intricacies underlying natural aging remain elusive. Here we presented a data...

2025-08-29 | MTBLS10642 | MetaboLights

Proteome analysis of adult mouse brain capillaries

Isolated brain capillaries are essential for analyzing the changes of protein expressions at the blood-brain barrier (BBB) under pathological conditions. The standard brain capillary isolation methods require the use of at least 5 mouse brains in order to obtain a sufficient amount and purity of bra...

ORGANISM(S): Mus Musculus (mouse)

2023-07-12 | PXD041770 | JPOST Repository

Proteome analysis of neonatal mouse brain and brain capillaries

The functions and protein expressions of the blood-brain barrier are changed during brain development after birth. The purpose of the present study was to develop a method to isolate brain capillaries from a single frozen neonatal mouse brain and elucidate the enrichment of brain capillaries by quan...

ORGANISM(S): Mus Musculus (mouse)

2023-07-12 | PXD039296 | JPOST Repository

High resolution analysis of genomic imprinting in the embryonic and adult mouse brain AND Sex-specific imprinting in the mouse brain

Genomic imprinting results in the preferential expression of the paternal, or maternal allele of certain genes. We have performed a genome-wide characterization of imprinting in the mouse embryonic and adult brain using F1 hybrid mice generated from reciprocal crosses of CASTEiJ and C57BL/6J mice. ...

ORGANISM(S): Mus musculus

2010-07-08 | E-GEOD-22131 | biostudies-arrayexpress

Cell-type and brain-region resolved mouse brain proteome

To understand the complexity of the brain, connectome and transcriptome maps of high resolution are being generated, but an equivalent catalogue of the brain proteome is lacking. To provide a starting point, we have performed an in-depth proteome analysis of the adult mouse brain, its major regions ...

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2020-02-08 | MSV000084941 | MassIVE

Mouse brain MALDI-imaging proteomics profiling

We developed and validated ‘HIT-MAP’ (High-resolution Informatics Toolbox in MALDI-MSI Proteomics), an open-source bioinformatics workflow using peptide mass fingerprint analysis and a dual scoring system to computationally assign peptide and protein annotations to high mass resolution MSI datasets,...

ORGANISM(S): Bos taurus (Bovine) Mus musculus (Mouse)

2021-05-17 | PXD025486 | Pride

An Anatomically Resolved Comprehensive Mouse Brain Proteome

A mouse brain protein atlas that covers 17 surgically distinctive neuroanatomical regions of the adult mouse brain, each less than 1mm3 in size.

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2016-06-01 | MSV000079789 | MassIVE

Mouse brain perivascular astrocyte endfoot proteome

Proteome analysis of isolated mouse brain blood vessels and perivascular astrocyte endfeet (PV-AEF) using DIA.

ORGANISM(S): Mus Musculus (mouse)

2023-11-04 | PXD037949 | JPOST Repository

Cell-type and brain-region resolved mouse brain proteome

ORGANISM(S): Mus musculus (Mouse)

2015-10-29 | PXD001250 | Pride

Brain regions Mouse Brain Neuron Q exactive Cns Oligodendrocyte Microglia Astrocyte

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