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ProteomicsPax6os1 pull-down in MIN6 cell lysate
Pull-down experiment to identify protein binding partners of the lncRNA Pax6os1 in mouse insulinoma cell line MIN6 using in-vitro transcribed RNA.
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD052133 | Pride
Mouse lncrna silac 
ProteomicsOne-shot analysis of translated mammalian lncRNAs with AHARIBO
A vast portion of the mammalian genome is transcribed as long non-coding RNAs (lncRNAs) acting in the cytoplasm with largely unknown functions. Surprisingly, lncRNAs have been shown to interact with ribosomes, encode uncharacterized proteins, or act as ribosome sponges. These functions still remain ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-09-09 | PXD022679 | Pride
Ribosome Proteogenomics Proteomics Ribo-seq Lncrna Rna Translatome Translation 
ProteomicsA disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis
Mutations in the human RMRP gene cause Cartilage Hair Hypoplasia (CHH), an autosomal recessive disorder characterized by skeletal abnormalities and impaired T-cell activation. RMRP encodes a non-coding RNA, which forms the core of the RNase MRP ribonucleoprotein complex. In budding yeast, RMRP cleav...
ORGANISM(S): Homo sapiens (Human) 
2021-03-30 | PXD025029 | Pride
Protein-rna interaction  rna-binding sites  uv crosslinking  mass spectrometry  genetic disease  cartilage hair hypoplasia  ribosome synthesis  t cell activation 
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