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ProteomicsProteomic-based identification of oocyte maturation-related proteins in mouse GV oocytes
In this study, we applied 1D SDS-PAGE and RP-LC-MS/MS to investigate the proteins stored in GV mouse oocytes. This high-performance strategy allowed us to define a set of 1405 different mouse GV oocyte proteins. It is confirmed that this study will help us to understand the diverse biological proces...
ORGANISM(S): Mus musculus (Mouse) 
2020-09-17 | PXD014314 | Pride
Mouse Gv oocytes Lc-ms/ms 
Proteomicsquantitative proteomic analysis of mouse oocyte of different chromatin configurations
Chromatin configuration serves as a principal indicator of GV (germinal vesicle)-stage oocyte quality. In this study, a quantitative proteomics method was applied to investigate the the underlying mechanisms governing the chromatin configuration.
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD048173 | Pride
Chromatin configuration Mouse Tmt Oocyte 
ProteomicsProtein profiling of mouse fully-grown oocyte
To verify the Ribo-seq data of mouse oocyte, we performed MS/MS on mouse fully-grown oocytes. And the results show that our Ribo-seq data well reflect the proteomic dynamics in the fully grown oocytes.
ORGANISM(S): Mus musculus (Mouse) 
2022-03-14 | PXD032229 | Pride
Mouse oocyte proteomic 
TranscriptomicsObjective molecular criteria for oocyte quality and developmental potential: a proteomic study in inbred mice
Current understanding of oocyte quality and developmental potential maintains that stochastic or epigenetic processes modulate the action of determinants that are laid in the oocyte during oogenesis. These determinants are considered to be rather conserved across mice, leading different strains of m...
ORGANISM(S): Mus musculus 
2016-06-18 | E-MTAB-5013 | biostudies-arrayexpress
ProteomicsMouse aging oocyte proteome comparison
Here we asked if oocyte proteomes are representative of the transcriptomes, how the abundance of specific genes’ mRNA and protein responds to maternal aging, and if oocyte aging presents the features characteristic of somatic aging. To address these questions on the proteomic level, we employed stab...
ORGANISM(S): Mus musculus (Mouse) 
2016-10-14 | PXD000512 | Pride
Mus musculus Embryonal carcinoma cells Spike-in Silac Oocyte 
ProteomicsProteomic profiling of RNA binding proteins in mouse oocyte
RNA-binding proteins (RBPs) control the fate of RNAs. Tissue regeneration and homeostasis depend on tissue-specific stem cells, but the scope of RBP involvementin these processes remains largely unknown. Here, we identified the RBP repertoire of the mouse oocytes.
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD034071 | Pride
Lc-ms/ms Mouse，oocyte，rbps 
TranscriptomicsMaternal age effect on mouse oocytes: new biological insight from proteomic analysis
The long-standing view of 'immortal germ line versus mortal soma' poses a fundamental question in biology concerning how oocytes age in molecular terms. A mainstream hypothesis is that maternal aging of oocytes has its roots in gene transcription. Investigating the proteins resulting from mRNA trans...
ORGANISM(S): Mus musculus 
2014-04-15 | E-GEOD-42959 | biostudies-arrayexpress
ProteomicsProteomic analysis of mouse oocytes identifies PRMT7 as reprogramming factor that replaces SOX2 in the induction of pluripotent stem cells
The inclusion of oocyte factors together with Yamanaka’s previously identified reprogramming factors (OCT4, SOX2, KLF4 with or without cMYC; OSK(M)) may facilitate the reprogramming process that leads to induced pluripotent stem cells (iPSCs). We previously applied label-free LC-MS/MS analysis to se...
ORGANISM(S): Mus musculus (Mouse) 
2016-05-31 | PXD003093 | Pride
Oocyte Reprogrammome Early embryo Development 
ProteomicsUltrasensitive proteomics depicted an in-depth landscape for the very early stage of mouse maternal-to-zygotic transition
Maternal-to-zygotic transition (MZT) is a conserved and fundamental process during which the maternal environment of oocyte transits to the zygotic genome driven expression program, and terminally differentiated oocyte and sperm are reprogrammed to totipotency. Metaphase II (MII) oocytes and zygotes...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-23 | PXD041399 | Pride
Mouse maternal-to-zygotic transition One-cell embryo Metaphase ii (mii) oocyte Ultrasensitive proteome technology 
ProteomicsTMT-MS Mouse oocyte proteomics dataset
This dataset contains quantitative tandem mass tag (TMT)-based proteomic profiling of mouse oocytes across defined experimental conditions. 500, fully grown, prophase I-arrested oocytes were isolated from young adult females and matured in vitro to metaphase II eggs.
ORGANISM(S): Mus musculus (Mouse) 
2026-06-06 | PXD076290 | Pride
Mouse oocytes 
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