Mouse spermatids

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Protein phosphorylation landscape of mouse spermatids during spermiogenesis

Tadpole-shaped sperm is formed from round spermatid by spermiogenesis, a process with dramatic morphological changes in the final stage of spermatogenesis in testis. Protein phosphorylation, as one of the most important post-translational modifications, can regulate spermiogenesis, however, there is...

ORGANISM(S): Mus musculus (Mouse)

2019-03-29 | PXD011890 | Pride

Quantitative proteomics analysis of Stra8-Pdcd5-/- mouse elongating spermatids

In order to investigate the molecular mechanism of PDCD5 in the regulation of spermatids development, elongating spermatids from Pdcd5F/F and Stra8-Pdcd5-/- mice were collected for quantitative proteomics analysis using TMT-based liquid chromatography-tandem mass spectrometry (LC-MS/MS) approach. A ...

ORGANISM(S): Mus musculus (Mouse)

2026-01-08 | PXD067835 | Pride

Pdcd5 Quantitative proteomics Tmt Mouse Elongating spermatids

TMT-based proteomics analysis of proteome changes in Ck137956-/- mouse round spermatids

The proteome changes were quantified in Ck137956-/- mouse round spermatids using TMT 6-plex by LC-MS/MS.

ORGANISM(S): Mus musculus (Mouse)

2023-04-01 | PXD036804 | Pride

Mouse Round spermatids Tmt Ck137956-/-

Small non-coding RNA expression in mouse elongated spermatids

In order to discover novel small RNAs expressed in elongated spermatids, we isolated elongated spermatids from mouse testis. The small RNA fraction (18-40nt) was cloned and sequenced from total RNA. RNAs extracted from elongated spermatids were used for high throughput sequencing analysis

ORGANISM(S): Mus musculus

2013-01-31 | E-GEOD-40397 | biostudies-arrayexpress

Expression data from shMiwi/shCaf1 transduced mouse elongating spermatids

We reasoned that the pi-RISC, by virtue of the enormous sequence portfolio of piRNAs, might mediate elimination of a large variety of mRNAs in late stages of spermiogenesis. Both Miwi-null and Caf1-null mice showed early spermiogenic arrest, preventing us from determining the role of MIWI and CAF1 i...

ORGANISM(S): Mus musculus

2014-07-11 | E-GEOD-59291 | biostudies-arrayexpress

Microarray analysis of purified germ cells in mouse

Microarray analysis of purified pachytene spermatocytes and round spermatids. Each stage was examined in wild type and RNF8 knockout mice in two biological replicates. We performed microarray analysis using Affymetrix Gene 1.0 ST Arrays with purified pachytene spermatocytes and round spermatids. Pac...

ORGANISM(S): Mus musculus

2013-01-04 | E-GEOD-39302 | biostudies-arrayexpress

Round Spermatids and Pachytene Spermatocytes

Mouse Round Spermatids (Sptd) and Pachytene Spermatocytes (Spcy)

ORGANISM(S): Mus musculus

2010-06-10 | E-GEOD-1768 | biostudies-arrayexpress

Bromodomain-dependent stage-specific male genome programming by Brdt [ChIP-Seq]

Male germ cell differentiation is a highly regulated multistep process initiated by the commitment of progenitor cells into meiosis and characterized by major chromatin reorganizations in haploid spermatids. We report here that a single member of the double bromodomain BET factors, Brdt, is a master...

ORGANISM(S): Mus musculus

2012-08-30 | E-GEOD-39908 | biostudies-arrayexpress

Ribosome Sequencing of Testicular Spermatids in Mex3d Knockout and Wild-Type Mice

Using isolated and purified round and elongated spermatids from the testes, Ribosome sequencing was performed to assess the impact of MEX3D protein deficiency on RNA metabolism in spermiogenesis.

ORGANISM(S): Mus musculus

2026-03-01 | E-MTAB-14988 | biostudies-arrayexpress

TMT-based phosphoproteomics and proteomics analysis of spermatids

We characterized the dynamic protein phosphorylation profiles of spermatids across four different developing steps.

ORGANISM(S): Mus musculus (Mouse)

2025-12-08 | PXD063123 | Pride

Mouse Tmt Phosphorylation Spermatids

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