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MetabolomicsMulti-omics Mechanistic Analysis of Efficient Lignocellulose Degradation by Pholiota adiposa Strain YAHS

Abstract This study focused on elucidating the lignocellulose degradation mechanism of Pholiota adiposa strain YAHS, aiming to provide theoretical basis and microbial resources for straw biorefining. Using the aniline blue-guaiacol plate screening method, 11 fungal strains were isolated from the ...

2025-10-12 | MTBLS13121 | MetaboLights
TranscriptomicsRole of mRNA stability during bacterial adaptation
Bacterial adaptation involves extensive cellular reorganization. In particular, growth rate adjustments are associated with substantial modifications of gene expression and mRNA abundance. In this work we aimed to assess the role of mRNA degradation during such variations. A genome-wide transcript...
ORGANISM(S): Lactococcus lactis 
2014-06-16 | E-GEOD-43875 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of mRNA degradation reveals Xrn1-dependent buffering of transcript levels
The rates of mRNA synthesis and degradation determine cellular mRNA levels and can be monitored by comparative Dynamic Transcriptome Analysis (cDTA) that uses non-perturbing metabolic RNA labeling. Here we present cDTA data for 46 yeast strains lacking genes involved in mRNA degradation and metaboli...
ORGANISM(S): Schizosaccharomyces pombe 
2013-10-18 | E-MTAB-1525 | biostudies-arrayexpress
TranscriptomicsThe RDE-10/RDE-11 complex triggers RNAi induced mRNA degradation by association with target mRNA in C. elegans
The molecular mechanisms for target mRNA degradation in C. elegans undergoing RNA interference (RNAi) are not fully understood. Using a combination of genetic, proteomic and biochemical approaches, we report a divergent RDE-10/RDE-11 complex that is required for RNAi in C. elegans. The RDE-10/RDE-...
ORGANISM(S): Caenorhabditis elegans 
2012-04-25 | E-GEOD-36494 | biostudies-arrayexpress
TranscriptomicsThe roles of 3’-exoribonucleases and the exosome in trypanosome mRNA degradation
The roles of 3’-exoribonucleases and the exosome in trypanosome mRNA degradation; 30 min after actinomycin D +sinefungin, RNAi against CAf1, CNOT10, PAN2. These are really old data that hadn't been deposited.The datasets called RNA1, RNA2, RNA3 and RNA4 are almost certainly, from their location in t...
ORGANISM(S): Trypanosoma brucei brucei 
2021-03-11 | E-MTAB-10260 | biostudies-arrayexpress
TranscriptomicsDecapped mRNAs during Arabidopsis Early Flower Development
The composition of the transcriptome is regulated by both mRNA synthesis and degradation. One route for mRNA decay is through 5’ decapping, which can be initiated by decapping enzymes and small RNAs. Although decapped RNAs are an important intermediate for mRNA decay, their identity and abundance ...
ORGANISM(S): Arabidopsis thaliana 
2008-10-10 | E-GEOD-12043 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of mRNA decay intermediates in Saccharomyces cerevisiae
The general pathways of eukaryotic mRNA decay occur via deadenylation followed by 3’ to 5’ degradation or decapping, although some endonuclease sites have been identified in metazoan mRNAs. To determine the role of endonucleases in mRNA degradation in Saccharomyces cerevisiae, we mapped 5’ monophosp...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-17 | E-GEOD-33712 | biostudies-arrayexpress
TranscriptomicsYeast mRNA decay analysis after addition of 3 µ/mL thiolutin
Time course after the addition of the transcriptional inhibitor thiolutin at 3µg/mL to an exponential growing culture of S. cerevisiae in YPD. Total RNA from BQS252 yeast strain (Mat a, ura 3-52 derived from FY1679) growing in exponential phase in YPD was extracted at different times after thioluti...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-25 | E-GEOD-7261 | biostudies-arrayexpress
TranscriptomicsRNA degradation in proliferating and differentiated C2C12 muscle precursor cells analyzed on Affymetrix exon arrays
Steady-state RNA levels are a result of RNA synthesis and degradation. The importance of transcription-factor mediated induction or repression of mRNA synthesis is well established, but the role and mechanisms of RNA degradation are less well understood. We globally evaluated the RNA decay rates in ...
ORGANISM(S): Mus musculus 
2010-09-22 | E-GEOD-14387 | biostudies-arrayexpress
TranscriptomicsmRNA degradation in Mycobacterium tuberculosis
This SuperSeries is composed of the following subset Series: GSE36341: mRNA degradation in Mycobacterium tuberculosis under aerobic conditions GSE36342: mRNA degradation in Mycobacterium smegmatis under aerobic conditions GSE36343: mRNA degradation in Mycobacterium tuberculosis during cold and hypox...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2012-03-08 | E-GEOD-36345 | biostudies-arrayexpress
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