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ProteomicsQuantitative proteomic characterization of lung-MSC and bone marrow-MSC using DIA-mass spectrometry
Mesenchymal stromal cells (MSC) are ideal candidates for cell therapies, due to their immune-regulatory and regenerative properties. We have previously reported that lung-derived MSC are tissue-resident cells with lung-specific properties compared to bone marrow-derived MSC. Assessing relevant molec...
ORGANISM(S): Homo sapiens (Human) 
2018-10-18 | PXD006419 | Pride
Human 
ProteomicsEffect of MSC and MSC-derived extracellular vesicles on human blood coagulation
Mesenchymal stem cells (MSC) have emerged as potent therapeutic tool for a number of pathologies, including immune ones. However, unwelcome effects of MSC on the blood coagulation were revealed in some cases, which require more in-depth analysis. In this study, we explored the trombotic properties o...
ORGANISM(S): Homo sapiens (Human) 
2019-03-26 | PXD012768 | Pride
Human Mesenchymal stem cells Vesicles 
TranscriptomicsExpression data from MSC-treated monocytes
Chronic inflammation leading to pro-inflammatory macrophage infiltration contributes to the pathogenesis of type 2 diabetes and subsequently the development of diabetic nephropathy. Mesenchymal stem cells (MSCs) possess unique immunomodulatory and cytoprotective properties making them an ideal candi...
ORGANISM(S): Homo sapiens 
2015-11-10 | E-GEOD-65561 | biostudies-arrayexpress
ProteomicsCytokine Priming Enhances the Antifibrotic Effects of Mesenchymal Stromal Cells Conditioned Medium Via Fibrogenic Myofibroblasts Elimination and Extracellular Matrix Degradation.
Fibrosis is a pathological scarring process characterized by persistent myofibroblasts activation with excessive accumulation of extracellular matrix (ECM). Fibrotic disorders represent an increasing burden of disease-associated morbidity and mortality worldwide for which there are limited therapeut...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051586 | Pride
Msc Myofibroblasts Multipotent mesenchymal stromal cells Fibrosis Conditioned medium Extracellular matrix 
TranscriptomicsPredicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1
Mesenchymal stromal cells (hMSCs) are advancing into the clinic but the therapeutic efficacy of hMSCs faces the problem of donor variability. In bone tissue engineering, no reliable markers have been identified which are able to predict the bone-forming capacity of hMSCs prior to implantation. To th...
ORGANISM(S): Homo sapiens 
2018-10-04 | E-MTAB-7210 | biostudies-arrayexpress
UnknownPPARβ/δ-dependent MSC metabolism determines their immunoregulatory properties.
Not available
S-EPMC7351754 | biostudies-literature
TranscriptomicsThe human nose harbours a niche of olfactory ecto-mesenchymal stem cells displaying neurogenic and osteogenic properties
We previously identified multipotent stem cells within the lamina propria of the human olfactory mucosa, located in the nasal cavity. We also demonstrated that this cell type differentiates into neural cells and improves locomotor behavior after transplantation in a rat model of Parkinson’s diseas...
ORGANISM(S): Homo sapiens 
2010-10-08 | E-GEOD-24598 | biostudies-arrayexpress
UnknownTherapeutic Features and Updated Clinical Trials of Mesenchymal Stem Cell (MSC)-Derived Exosomes.
Not available
S-EPMC7916919 | biostudies-literature
ProteomicsQuantitative proteomic analysis of MSC and electrically stimulated MSC (epMSC) secretomes
This study aimed to investigate the effects of electrical stimulation (ES) on the secretome of mesenchymal stem cells (MSCs). Using quantitative proteomics, we identified a total of 435 proteins secreted by MSCs and ES-treated MSCs (epMSCs), among which 418 were common between groups, with 14 and 8 ...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD066035 | Pride
Human Stem cell 
UnknownSulfated Alginate Hydrogels Prolong the Therapeutic Potential of MSC Spheroids by Sequestering the Secretome.
Not available
S-EPMC8568671 | biostudies-literature
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