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Here we report that the histone variant macroH2A acts as a barrier to induced pluripotency. Using fibroblasts isolated from macroH2A double knockout mice, we observed enhanced reprogramming efficiency compared to fibroblasts from wild type animals. We further show that macroH2A isoforms act synergis...
ORGANISM(S): Mus musculus 
The histone variant macroH2A generally associates with transcriptionally inert chromatin, however the factors that regulate its chromatin incorporation remain elusive. Here, we identify the SWI/SNF helicase, ATRX, as a novel macroH2A interacting protein. Unlike its role in assisting H3.3 chromatin d...
ORGANISM(S): Homo sapiens 
These two projects are about the proteome of wild type E. coli K-12 NCM3722 strain (RE198LQ) and its rpoS-null strain (XA00994LQ). Both projects include replicates of two conditions, the normal conditions and (p)ppGpp overproduction conditions via RelA* OE.
ORGANISM(S): Escherichia coli O104:H4 str. 01-09591 
2023-12-20 | PXD042250 | Pride
This project is about the proteomes of wild type B. subtilis and its codY-null strain (The organism at right side was mislabeled as "E. coli")
ORGANISM(S): Escherichia coli 
2025-11-10 | PXD055309 | Pride
This project is about the proteomes of wild type B. subtilis and its codY-null strain (The organism at right side was mislabeled as "E. coli")
ORGANISM(S): Escherichia coli 
2025-11-10 | PXD052459 | Pride
This project is about the proteomes of wild type cells (WT) and spo0A-null strain of B. subtilis during exponential growth in mannose medium. B2 & B4 corresponds to the wild type cells (two biological replicate samples) and B6 & B8 corresponds to spo0A-null data (two biological replicate samples).
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2023-05-10 | PXD039192 | Pride
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