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The post-translational regulation of protein function is involved in most cellular processes. As such, synthetic biology tools that operate at this level provide opportunities for manipulating cellular states. Here, we deploy a proximity-triggered protein trans-splicing technology to enable the time...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-10-06 | PXD044530 | Pride
Elucidating the physiological binding partners of histone post-translational modifications (hPTMs) – i.e. their interactomes – is key to understanding fundamental epigenetic regulatory pathways. Here we use a synthetic biology approach to set a series of hPTM-controlled photo-affinity traps in nativ...
ORGANISM(S): Homo sapiens (Human) 
2020-03-27 | PXD017447 | Pride
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