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With the use of iTRAQ technique, a multifactorial comparative proteomic study can be performed. In this study, to obtain an overview of ethanol, CYP2E1 and gender effects on liver injury and gain more insight into the underlying molecular mechanism, mouse liver proteomes were quantitatively analyze...
ORGANISM(S): Mus musculus (Mouse) 
2014-04-11 | PXD000635 | Pride
Fish gills are not only the respiratory organ, but also essential for ion-regulation, acid-base control, detoxification, waste excretion and host defense. Multifactorial gill diseases are common in farmed Atlantic salmon, and still poorly understood. Understanding gill pathophysiology is of paramoun...
ORGANISM(S): Salmo salar (Atlantic salmon) 
2024-01-26 | PXD044533 | Pride
The development of ultrasensitive proteomic methods for the detection of proteins — potential tumor biomarkers — remains one of the key challenges in modern biomedicine. Based on data obtained using high-sensitivity technologies and the integration of proteomic and metabolomic layers of genome-encod...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD068982 | Pride
Tumor and non-tumor tissues from 19 cases of colorectal cancer were examined using DIA-based mass spectrometry. A total of 11,833 proteins were identified, including 531 of the 748 cancer-associated proteins defined in the Catalogue of Somatic Mutations in Cancer. In the comparative analysis between...
ORGANISM(S): Homo Sapiens (human) 
Porphyromonas gingivalis and Treponema denticola are periodontalpathogens that are associated with the severity and progression of periodontal diseases. this study investigates the gene expression of Treponema denticola during co-culture with Porphyromonas gingivalis.
ORGANISM(S): Treponema denticola 
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