Sort   by:  
 Page size 
ProteomicsTAG-TMTpro, a hyperplexing quantitative approach for high-throughput proteomic studies
Isobaric labeling is the most widely used multiplexing quantitative approach in proteomic studies, enabling the comparison of up to 18 samples in a single MS analysis. Expanding the multiplexing capacity is of great necessity for high-throughput proteomic studies. Herein, we establish a novel TAG-TM...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2022-10-14 | PXD033711 | Pride
Proteomics Multiplexing quantitative approach Tmtpro labeling 
ProteomicsSample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression
Targeted proteomics enables hypothesis-driven research by measuring the cellular expression of protein cohorts related by function, disease, or class after perturbation. Here, we present a pathway-centric approach and an assay builder resource for targeting entire pathways of proteins selected from ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2022-08-11 | MSV000090110 | MassIVE
Proteomics102-Plex Approach for Accurate and Multiplexed Proteome Quantification
Numerous hyperplexing approaches have been developed to meet the demand for large-scale basic and clinical analysis. Currently, the analysis capacity has expanded to up to 54 samples within a single experiment by utilizing different isotopic and isobaric reagent combinations. In this report, we prop...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2024-01-15 | PXD042398 | Pride
Multiplexing Quantitative proteomic analysis 102-plex approach 
ProteomicsData-independent acquisition protease-multiplexing enables increased proteome sequence coverage across multiple fragmentation modes
The use of multiple proteases has been shown to increase protein sequence coverage in proteomics experiments, but due to the additional sample preparation and analysis time required, it has not been widely adapted in routine proteomic workflows. While data-independent acquisition (DIA) has been prim...
ORGANISM(S): Homo sapiens (Human) 
2022-03-18 | PXD027242 | Pride
Dia Gluc Multiplexing Aspn 
ProteomicsA Tribrid Hyperplexing approach for Large-scale Quantitative Proteomic Analysis
Isobaric labeling has emerged as an indispensable quantitative proteomic approach for its unprecedented multiplexing capacity in a single analysis. Currently, different hyperplexing approaches have been developed to meet the need for increasing sample numbers in large-scale cohort analysis. In this ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2023-03-17 | PXD037498 | Pride
Tmtpro Ibt Tmt Hyperplexing Quantitative proteomics 
UnknownTomographic fluorescence lifetime multiplexing in the spatial frequency domain.
Not available
S-EPMC6457659 | biostudies-literature
ProteomicsOptimal analytical strategies for sensitive and quantitative phosphoproteomics using TMT-based multiplexing
In large-scale quantitative mass spectrometry (MS)-based phosphoproteomics, isobaric labeling with tandem mass tags (TMTs) coupled with offline high-pH reversed-phase peptide chromatographic fractionation maximizes depth of coverage. To investigate to what extent limited sample amounts affects sensi...
ORGANISM(S): Homo sapiens (Human) 
2022-06-28 | PXD031277 | Pride
Tandem mass tags Phosphoproteomics Optimization High-ph fractionation Isobaric labeling 
UnknownData-Independent Acquisition Protease-Multiplexing Enables Increased Proteome Sequence Coverage Across Multiple Fragmentation Modes.
Not available
S-EPMC9035370 | biostudies-literature
UnknownIncreased N,N-Dimethyl Leucine Isobaric Tag Multiplexing by a Combined Precursor Isotopic Labeling and Isobaric Tagging Approach.
Not available
S-EPMC6314838 | biostudies-literature
GenomicsGenome-wide comparison of DNA hydroxymethylation in mouse embryonic stem cells and neural progenitor cells by relative quantitative hMeDIP-seq
DNA hydroxymethylation (5hmC) represents a new layer of epigenetic regulation in addition to DNA methylation (5mC). The genome-wide patterns of 5hmC distribution in many tissues and cells have recently been revealed by hydroxymethylated DNA immunoprecipitation (hMeDIP) followed by high throughput se...
ORGANISM(S): Mus musculus 
2013-03-08 | E-GEOD-40810 | biostudies-arrayexpress
Sort   by:  
 Page size