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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
TranscriptomicsNsaRS is a Cell-Envelope-Stress Sensing Two-Component System of Staphylococcus aureus
S. aureus possesses 16 two-component systems (TCS), two of which (GraRS & NsaRS) belong to the intramembrane-sensing histidine kinase (IM-HK) family, conserved within the firmicutes. NsaRS has recently been documented as being important for nisin-resistance in S. aureus. In this study we present a d...
ORGANISM(S): Staphylococcus aureus 
2011-05-16 | E-GEOD-27061 | biostudies-arrayexpress
UnknownThe World Health Organization ageism towards older persons scale: preliminary validation of a novel measure of ageist stereotypes, prejudices, and discrimination in four different countries.
Not available
S-EPMC12831184 | biostudies-literature
UnknownA consensus guideline for antipsychotic drug use for dementia in care homes. Bridging the gap between scientific evidence and clinical practice.
Not available
S-EPMC4582430 | biostudies-literature
ProteomicsCDK1 and CDK2 regulate NICD1 turnover and the periodicity of the segmentation clock
All vertebrates share a segmented body axis. Segments form from the rostral end of the presomitic mesoderm (PSM) with a periodicity that is regulated by the segmentation clock. The segmentation clock is a molecular oscillator that exhibits dynamic clock gene expression across the PSM with a periodic...
ORGANISM(S): Homo sapiens (Human) 
2020-03-24 | PXD013038 | Pride
Notch Signalling Cell cycle Fbxw7 Somitogenesis Phosphorylation 
GenomicsExome sequencing to identify predisposition to Wilms tumour
To identify new Wilms tumor predisposition genes, we performed whole-exome paired-end sequencing of lymphocyte DNA from 12 affected individuals from six unrelated, non-syndromic Wilms tumor families in which known causes had been excluded. We prepared DNA libraries from 1.5 mg blood-derived genomic...
EGAS00001000904 | EGA
Genomicsena-DATASET-ICR-GSR-09-09-2014-10:48:45:936-187 - samples
Exome sequencing of lymphocyte DNA from 12 affected individuals from six unrelated, non-syndromic Wilms tumor families.
EGAD00001001003 | EGA
GenomicsICR-GSR
Data Access Committee EGAC00001000235
EGAC00001000235 | EGA
ProteomicsNCLX proximity biotinylation screen
The mitochondrial sodium/calcium exchanger, NCLX, is critical to maintaining mitochondrial calcium homeostasis, yet little remains known about the mechanisms regulating its function. Here, we performed proximity biotinylation screening to identify the NCLX interactome and potential protein regulator...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000093004 | MassIVE
UnknownMatched cohort study of therapeutic strategies to prevent preschool wheezing/asthma attacks.
Not available
S-EPMC6294169 | biostudies-literature
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