Sort   by:  
 Page size 
ProteomicsComparison of the skeletal muscle proteomes in wt and hBAG3P209L overexpressing mice
Myofibrillar myopathy-6 (MFM6) is rare, autosomal dominant neuromuscular disease that is characterised by devastating childhood muscular dystrophy, restrictive cardiomyopathy, and respiratory insufficiency. MFM-6 is caused by single base mutation in the gene encoding the co-chaperone BAG3 (Bcl-2 ass...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-11 | PXD047942 | Pride
Myofibrillar myopathy-6  mouse model  proteome  skeletal muscle Bag3p209l Bag3 
ProteomicsProteome and transcriptome profiling of equine myofibrillar myopathy identifies diminished peroxiredoxin 6 and enhanced cysteine metabolic pathways
Equine myofibrillar myopathy (MFM) causes exertional muscle pain and is characterized by myofibrillar disarray and ectopic protein aggregates of unknown origin. To investigate the pathophysiology of MFM, we compared the skeletal muscle proteome and 3 h post-exercise transcriptome of gluteal muscle i...
ORGANISM(S): Equus caballus (Horse) 
2019-11-12 | PXD009362 | Pride
Myopathy Horse Antioxidant Proteome 
UnknownPersonalized allele-specific CRISPR-Cas9 strategies for myofibrillar myopathy 6.
Not available
S-EPMC10863003 | biostudies-literature
UnknownProteome and transcriptome profiling of equine myofibrillar myopathy identifies diminished peroxiredoxin 6 and altered cysteine metabolic pathways.
Not available
S-EPMC6337024 | biostudies-literature
TranscriptomicsEffect of Smyd1 conditional knockout on gene expression in skeletal muscle
Transcriptome analysis by RNA-seq of tibialis anterior muscle from control and Smyd1 myocyte-specific conditional knockout mice at 6 weeks of age. Smyd1 is a methyltransferase specifically expressed in striated muscle and CD8+ T cells. Smyd1 deficiency resulted in centronuclear myopathy primarily ...
ORGANISM(S): Mus musculus 
2016-04-05 | E-GEOD-71679 | biostudies-arrayexpress
UnknownMitochondrial dysfunction in myofibrillar myopathy.
Not available
S-EPMC5066370 | biostudies-literature
UnknownSuspected myofibrillar myopathy in Arabian horses with a history of exertional rhabdomyolysis.
Not available
S-EPMC4833696 | biostudies-literature
TranscriptomicsArabidopsis EDM2 Promotes IBM1 Distal Polyadenylation and Regulates Genome DNA Methylation Patterns [RNA-Seq]
A forward genetics screen led to the identification of the putative chromatin regulator EDM2 as a cellular anti-silencing factor and regulator of genome DNA methylation patterns. EDM2 contains a composite PHD finger domain that recognizes both active H3K4 and repressive H3K9 methylation marks at the...
ORGANISM(S): Arabidopsis thaliana 
2013-10-29 | E-GEOD-51763 | biostudies-arrayexpress
UnknownViral-mediated expression of desmin mutants to create mouse models of myofibrillar myopathy.
Not available
S-EPMC3599656 | biostudies-literature
UnknownMasseter muscle myofibrillar protein synthesis and degradation in an experimental critical illness myopathy model.
Not available
S-EPMC3976271 | biostudies-literature
Sort   by:  
 Page size