Sort   by:  
 Page size 
ProteomicsStudy of endogenous interactome of Myosin VI
Immunoprecipitation of endogenous Myosin VI in Human Cell Lines (Caco-2, HeLa, MCF10A, MDA-MB-231) and identification of true interactors by mass spectrometry
ORGANISM(S): Homo sapiens (Human) 
2021-07-08 | PXD026697 | Pride
Myosin vi Mcf 10a Hela Mda-mb-231 Caco-2 
ProteomicsNuclear myosin VI maintains replication fork stability
The actin cytoskeleton is of fundamental importance for cellular structure and plasticity. However, abundance and function of filamentous (F-) actin in the nucleus are still controversial. Here we show that the actin-based molecular motor myosin VI contributes to the stabilization of stalled or reve...
ORGANISM(S): Homo sapiens (Human) 
2023-05-04 | PXD035394 | Pride
Myosin vi Wrnip1 Darpins Fork stability Dna replication stress 
TranscriptomicsMyo6 regulate transcriptional pause release
Global run-on sequencing analyses of murine T cells with or without Myosin VI were performed to determine the effect of anti-CD3 stimulation and loss of Myosin VI on the transcription elongation
ORGANISM(S): Mus musculus 
2015-01-28 | E-MTAB-2381 | biostudies-arrayexpress
ProteomicsHow Myosin VI Traps its Off-State, is Activated and Dimerizes
Myosin VI (Myo6) is the only minus-end directed nanomotor on actin, allowing it to uniquely contribute to numerous cellular functions. As for other nanomotors, proper functioning of Myo6 relies on precise spatio-temporal control of motor activity via a poorly defined off-state and interactions with ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD044767 | Pride
Myosin vi Human Clms Cross linking mass spectromety 
GenomicsExpression profiling by high throughput sequencing of Myosin VI
Expression profiling by high throughput sequencing of Myosin VI
PRJNA1279160 | ENA
GenomicsSingle molecule nanoscopy reveals that nuclear myosin VI regulates the spatial organization of mammalian transcription initiation
Single molecule nanoscopy reveals that nuclear myosin VI regulates the spatial organization of mammalian transcription initiation
PRJNA628703 | ENA
TranscriptomicsSingle molecule nanoscopy reveals that nuclear myosin VI regulates the spatial organization of mammalian transcription initiation
During transcription, RNA Polymerase II (RNAPII) is spatially organised into clusters that correlate with transcription activity. However, the assembly, organisation and stability of these transcription units remains unknown. Here, we have combined single molecule imaging with genomics approaches in...
ORGANISM(S): Homo sapiens 
2020-05-31 | GSE149448 | GEO
GenomicsNuclear Myosin VI stabilises Ku-associated DNA ends during nonhomologous end joining
Nuclear Myosin VI stabilises Ku-associated DNA ends during nonhomologous end joining
PRJNA1530528 | ENA
UnknownStructure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering.
Not available
S-EPMC6673701 | biostudies-literature
TranscriptomicsExpression profiling by high throughput sequencing of Myosin VI
Around 75% of breast cancer patients have estrogen receptor (ER) positive breast cancer. Endocrine-related therapies employed to treat these patients often fail due to resistance. Consequently, new therapeutic targets are needed. Myosin VI (MVI) is increasingly implicated in cancer and has been iden...
ORGANISM(S): Homo sapiens 
2026-01-13 | GSE300165 | GEO
Sort   by:  
 Page size