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Here we undertake the characterisation of Myst2 protein interactions in mouse embryonic stem cells by affinity purification and mass spectrometry using a Myst2-FTAP tagged cell line. This protein interaction study confirms that in mouse embryonic stem cells Myst2 is part of H3 and H4 histone acetyla...
ORGANISM(S): Mus musculus (Mouse) 
2017-08-22 | PXD005987 | Pride
MEAF6 is essential for proliferation and plays a role in the assembly of KAT7 complexes.
ORGANISM(S): Mus Musculus (mouse) 
We find that 499 genes are up-regulated and 457 are down-regulated in response to over-expression of JADE1, while 397 genes are up-regulated and 385 are down-regulated after HBO1 knock-down. For each condition - HBO1 siRNA treatment or JADE1 over-expression - two biological replicates were analyzed ...
ORGANISM(S): Homo sapiens 
This submission contains the mass spectrometry files for the manuscript by Feng et al. that describes the characterization of a protein complex containing BRPF3 and HBO1 in the regulation of DNA replication origins. This submission contains 3 IDA files for the following baits: empty 3XFLAG control, ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-11-19 | MSV000078943 | MassIVE
We used ChIP-seq technology in order to map chromatin binding sites of the HBO1 MYST complex in the RKO cell line. We obtained a significant enrichment of the HBO1 signal right after TSS regions of genes and also In the proximal promoter region, with no signal on TSS. This enrichment also correlates...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE33007: Genome-wide map of HBO1 in cancer derived human cell line GSE33220: Effects of the JADE-HBO1 complex on gene expression Refer to individual Series
ORGANISM(S): Homo sapiens 
HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
ORGANISM(S): Homo Sapiens (human) 
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