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ProteomicsPeptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA
MZB1 is an endoplasmic reticulum residential protein preferentially expressed in plasma cells, marginal zone and B1 B cells. Recent studies on murine B cells shows that it interacts with the tail piece of IgM and IgA heavy chain and promotes the secretion of these two classes of immunoglobulin. Howe...
ORGANISM(S): Homo sapiens (Human) 
2023-11-23 | PXD047044 | Pride
Post-translational modification Citrullination Mzb1 Rheumatoid arthritis 
GenomicsCo-chaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and b1 integrin function
Co-chaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and b1 integrin function
PRJNA484514 | ENA
UnknownMZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells.
Not available
S-EPMC7736851 | biostudies-literature
UnknownMZB1 regulates the immune microenvironment and inhibits ovarian cancer cell migration.
Not available
S-EPMC12086629 | biostudies-literature
GenomicsMZB1 knockout in human melanoma cells significantly modulates genes associated with cancer immune signaling
MZB1 knockout in human melanoma cells significantly modulates genes associated with cancer immune signaling
PRJNA1201597 | ENA
TranscriptomicsCo-chaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and b1 integrin function
Plasma cell differentiation involves coordinated changes in gene expression and functional properties of B cells. Here, we study the role of Mzb1, a Grp94 co-chaperone that is expressed in marginal zone (MZ) B cells and during the terminal differentiation of B cells to antibody-secreting cells (ASCs...
ORGANISM(S): Mus musculus 
2019-01-01 | GSE118124 | GEO
TranscriptomicsIntegrative array-based approach identifies MZB1 as a frequently methylated putative tumor-suppressor in hepatocellular carcinoma
This SuperSeries is composed of the following subset Series: GSE35311: Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor-suppressor in hepatocellular carcinoma (expression) GSE35312: Integrative array-based approach identifies MZB1 as a frequently methylated ...
ORGANISM(S): Homo sapiens 
2012-03-30 | E-GEOD-35313 | biostudies-arrayexpress
UnknownCochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function.
Not available
S-EPMC6187189 | biostudies-literature
UnknownPeptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA.
Not available
S-EPMC10716219 | biostudies-literature
UnknownPuerarin attenuates myocardial ischemic injury and endoplasmic reticulum stress by upregulating the Mzb1 signal pathway.
Not available
S-EPMC11350615 | biostudies-literature
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