Sort   by:  
 Page size 
ProteomicsMetabolic regulation of N-terminal acetylation in yeast
N-terminal (Nt) acetylation, catalyzed by N-terminal acetyltransferases (NATs), has emerged as an important co-translational modification in eukaryotes, and involves the transfer of the acetyl moiety from acetyl-CoA (Ac-CoA) to the α-amino group of a nascent polypeptide. Here, we report the first gl...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-09-07 | PXD004326 | Pride
Metabolism Acetyl coenzyme a Saccharomyces cerevisiae N-terminal acetylation N-terminomics 
ProteomicsGlobal profiling of acetylation reveals a new family with dual-specific lysine and N-terminal acetyltransferase activity in the plastids of Arabidopsis
Protein acetylation is a universally conserved modification occurring on N-termini (N--acetylation, NTA) and on internal lysines residues (-lysine-acetylation, KA). So far, NTA and KA were known to be supported by distinct families of enzymes (NATs and KATs, respectively), despite most of them sha...
ORGANISM(S): Escherichia Coli 
2020-07-07 | PXD015875 | JPOST Repository
ProteomicsFast light changes promote distinct responses of plastid protein acetylation marks
Protein acetylation is a key recurring co- and posttranslational modification. How different types of acetylation respond to the same environmental stress is unknown. A member of the newly discovered family of plastid acetyltransferases (GNAT2), which is featuring both lysine- and N-terminal acetyl...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2024-08-19 | PXD040517 | JPOST Repository
Proteomicsplasma membrane anchored NAA60 N-terminal acetylation profiling in Arabidopsis thaliana
N-terminal acetylation (NTA) is one of the most abundant protein modifications in eukaryotes and is catalysed in humans by seven N-acetyltransferases. AtNAA60 localizes to the plasma membrane in vivo by an α-helical membrane anchor at its C-terminus. In this study, we investigated the Arabidopsis th...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-07-15 | PXD016494 | Pride
Acetyltransferase N-acetylome N-terminal acetylation Quantitative proteomics Silpronaq 
ProteomicsN-terminal acetylome analysis reveals an expanded substrate profile for the NatC N-terminal acetyltransferase complex in yeast
N-terminal acetylation is a conserved protein modification among eukaryotes, and the yeast Saccharomyces cerevisiae is a valuable model system for studying this modification. The enzymes responsible for the bulk of protein N-terminal acetylation in S. cerevisiae are the N-terminal acetyltransferases...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-01-26 | PXD039544 | Pride
Natc N-terminal acetylation N-alpha-acetyltransferase 30 (naa30) Saccharomyces cerevisiae N-terminal acetylome N-terminal cofradic N-terminomics. 
ProteomicsN-terminal acetylation in Arabidopsis thaliana, and the effects of Naa10/15 or HypK knock-outs
This project is about the study of the effects of several proteins on the proteome of Arabidopsis thaliana, and more specifically on the N-terminal acetylome of this plant. To this end were analysed KO samples of either an N-alpha acetyltransferase (Naa10 or Naa15) or the chaperonne protein HypK.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-08-12 | PXD023195 | Pride
Naa15 Proteomics Arabidopsis thaliana Mass spectrometry N-terminal acetylation Hypk Naa10 
ProteomicsGlobal acetylation profiling for the Arabidopsis thaliana plasma membrane anchored NAA60 N-terminal acetyltransferase
N-terminal acetylation is one of the most abundant protein modifications in eukaryotes and is catalysed in humans by seven N-terminal acetyltransferases. AtNAA60 is localized in vivo at the plasma membrane by an α-helical membrane anchor at its C-terminus. In this study, we investigated the Arabidop...
ORGANISM(S): Escherichia coli 
2020-07-15 | PXD016533 | Pride
Acetyltransferase N-acetylome N-terminal acetylation Quantitative proteomics Silpronaq Gap test 
ProteomicsStructural, molecular and cellular impact of the Ogden syndrome mutant N-terminal acetyltransferase hNaa10-Ser37Pro
Abstract still has to be written. The obtained peptide mixtures were introduced into an LC-MS/MS system, the Ultimate 3000 (Dionex, Amsterdam, The Netherlands) in-line connected to an LTQ Orbitrap XL mass spectrometer (Thermo Fisher Scientific, Bremen, Germany). Samples were first loaded on a trapp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-13 | MSV000083564 | MassIVE
UnknownMolecular basis for N-terminal alpha-synuclein acetylation by human NatB.
Not available
S-EPMC7494357 | biostudies-literature
UnknownN-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing.
Not available
S-EPMC3778019 | biostudies-literature
Sort   by:  
 Page size