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ProteomicsProteomic changes of Naa20 knockdown in Arabidopsis thaliana
N-terminal acetyltransferase B (NatB) acetylates around 20% of the eukaryotic proteome and is crucial for protein function and organismal development. However, the regulatory roles of NatB-mediated N-terminal acetylation (NTA) in proteome stability and autophagy regulation remain unclear in plants. ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-03-01 | PXD066676 | Pride
Naa20 Ubiquitination Plants 
UnknownStructural basis of Naa20 activity towards a canonical NatB substrate.
Not available
S-EPMC7782713 | biostudies-literature
ProteomicsProteomic study of Naa20 inactivation in MEFs
This study focuses on the proteomic analysis of mouse embryonic fybroblasts where Naa20 can be inactivated, to observe its role in biological pathways and its effect on the N-terminal acetylation of proteins.
ORGANISM(S): Mus musculus (Mouse) 
2025-08-25 | PXD029641 | Pride
Mef Mus musculus Proteome Acetylation N-terminal Naa20 
UnknownNAA20-mediated ACF1 lactylation drives neuroblastoma progression through enhancing GCLM-dependent glutathione synthesis.
Not available
S-EPMC12906602 | biostudies-literature
UnknownMissense NAA20 variants impairing the NatB protein N-terminal acetyltransferase cause autosomal recessive developmental delay, intellectual disability, and microcephaly.
Not available
S-EPMC8553619 | biostudies-literature
UnknownNaa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1-AMPK-mTOR axis.
Not available
S-EPMC8080711 | biostudies-literature
ProteomicsYeast Nat Nt-acetylation SWATH MS
Yeast strains (wild type, Naa10 KO and Naa20 KO, resp: wt, natA-delta and natB-delta) were profiled for full proteome analysis by SWATH MS
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-12-15 | PXD015217 | Pride
Nt-acetylation Dia Nata Natb Swath ms Yeast 
ProteomicsN-terminal acetyaltion of Human JunB in yeast expressing all N-terminal acetyltransferases, no NatA enzyme or no NatB enzyne
Define the N-terminal status of overexpressed human JUNB in WT yeast strain, NAA10 Δ strain and NAA20 Δ strain.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-07-03 | PXD047612 | Pride
Junb N-terminal acetyltransferase 
ProteomicsDetermination of polyubiquitinated proteins enriched with UbiQaputre-Q matrix in the wild-type and naa20-cr1 mutant
To investigate the role of NatB-mediated N-terminal acetylation in regulating protein stability in Arabidopsis thaliana, polyubiquitinated proteins were determined by mass spectrometry in wild type (Col-0) and naa20-cr1 mutant after enrichment by UbiQaputre-Q matrix (Enzo life Sciences).Proteins wit...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-03-02 | PXD054814 | Pride
Natb N-terminal acetylation Ubiquitination Protein turnover N-terminal acetyltransferase 
TranscriptomicsDownregulation of N-terminal initiator methionine imprinting by NatB impacts growth and the response to osmotic stress in Arabidopsis
N-terminal acetylation (NTA) is one of the most abundant protein modifications in eukaryotes and is catalyzed in humans by seven Nα-acetyltransferases (NatA-F and NatH). Remarkably, the characterization of the plant Nat machinery and its biological relevance is still in its infancy, although NTA has...
ORGANISM(S): Arabidopsis thaliana 
2020-04-14 | GSE132978 | GEO
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