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ProteomicsNAA80-V5 interactor screen in HeLa and HAP1 cells
Actin is N-terminally acetylated by NAA80. We aimed to characterize the NAA80 interactome.
ORGANISM(S): Homo sapiens (Human) 
2020-09-25 | PXD021408 | Pride
N-terminal acetylation Cytoskeleton Acetylation Actin Protein modifications Nat Naa80 
ProteomicsNAA80-V5 interactor screen in HeLa and HAP1 cells
Actin is N-terminally acetylated by NAA80. We aimed to characterize the NAA80 interactome.
ORGANISM(S): Homo sapiens (Human) 
2020-07-16 | PXD020188 | Pride
N-terminal acetylation Cytoskeleton Acetylation Actin Protein modifications Nat Naa80 
Proteomicsnaa80 knockout zebrafish tissue proteomics
Investigation of actin N-terminal acetylation status in zebrafish with knockout alleles for Naa80, the actin N-terminal acetyltransferase.
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2024-09-26 | PXD046978 | Pride
Cytoskeleton N-terminal acetylation Actin Hearing loss Naa80 
ProteomicsNaa80 acetylates the actin N-terminus impacting the actin cytoskeleton and cell motility
Eukaryotic actins undergo several post-translational modifications during their maturation to enable a fully functional cytoskeletal network. A unique N-terminal processing is conserved in the animal kingdom and includes the removal of the first one or two amino acids as well as N-terminal acetylati...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD006856 | Pride
N-terminal acetylation Nat Actin Human 
UnknownPFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin.
Not available
S-EPMC7864067 | biostudies-literature
UnknownNaa80 is required for actin N-terminal acetylation and normal hearing in zebrafish.
Not available
S-EPMC11465159 | biostudies-literature
UnknownN-terminal acetylation of actin by NAA80 is essential for structural integrity of the Golgi apparatus.
Not available
S-EPMC7308165 | biostudies-literature
UnknownNAA80 bi-allelic missense variants result in high-frequency hearing loss, muscle weakness and developmental delay.
Not available
S-EPMC8599064 | biostudies-literature
UnknownStructural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80.
Not available
S-EPMC5924903 | biostudies-literature
UnknownNAA80 is actin's N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility.
Not available
S-EPMC5924898 | biostudies-literature
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