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MetabolomicsEffect of NAC154 transcription factor overexpression on the field grown poplar stem wood metabolome
Several xylem-associated regulatory genes have been identified that control processes associated with wood formation in poplar. Prominent among these are the NAC domain transcription factors (NACs). We evaluated the putative involvement of Populus NAC154, a co-ortholog of the Arabidopsis gene SND2, ...
2015-01-31 | MTBLS119 | MetaboLights
TranscriptomicsThe effects of NAC on gene expression in Nkx3.1-/- mouse prostate
We tested the effects of the antioxidant NAC (N-Acetyl-Cysteine) on gene expression in Nkx3.1-deficient mouse prostate. Mice that were homozygous null for Nkx3.1 were given NAC or plain water ad libidum for 13 weeks after weaning. Prostates were collected, RNA was harvested and reverse transcribed, ...
ORGANISM(S): Mus musculus 
2012-10-23 | E-GEOD-40352 | biostudies-arrayexpress
GenomicsGenome-wide identification of binding sites for NAC and YABBY transcription factors and co-regulated genes during soybean seedling development by ChIP-Seq and RNA-Seq.
In order to dissect the gene regulatory network during the functional transition of cotyledons from non-photosynthetic storage tissue to metabolically active photosynthetic tissue, we constructed ChIP-Seq libraries for NAC and YABBY transcription factors using pooled cotyledons from seedling develop...
ORGANISM(S): Glycine max 
2013-08-14 | E-GEOD-42422 | biostudies-arrayexpress
TranscriptomicsContribution of NAC transcription factors to plant adaptation to land
The development of cells specialized for water conduction or support is a striking innovation of plants that has enabled them to colonize land. The NAC transcription factors regulate differentiation of these cells in vascular plants. However, the path by which plants with these cells have evolved fr...
ORGANISM(S): Physcomitrella patens 
2014-05-23 | E-MTAB-4115 | biostudies-arrayexpress
ProteomicsEarly Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC
In this study, NAC was UV-crosslinked using the photo-crosslinking amino acid p-benzoyl-L-phenylalanine (pBPA) in order to determine specific interaction sites of the alphaNAC N-terminus in the native protein structure. Furthermore, quantitative chemical crosslinking coupled to mass spectrometry (q-...
ORGANISM(S): Homo sapiens (Human) Caenorhabditis elegans 
2019-07-25 | PXD011995 | Pride
Nac Structural mass spectrometry Uv-crosslinking Q-xl-ms 
TranscriptomicsNAC, Tiron and Trolox impair GBM tumorigenic cell survival by mechanisms independent from antioxidant activity
The aim of this study is to determine if, using antioxidant drugs, it is possible to interfere with the proliferative capabilities of the human glioblastoma (GBM) tumor-initiating cells (TICs). To establish which cellular processes are activated in GBM TICs by the antioxidants NAC, Tiron and Trolox,...
ORGANISM(S): Homo sapiens 
2014-03-04 | E-GEOD-44099 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human NHEK cells response to 2mM N-Acetyl-L-cystein (NAC) treatment - 1,12, 24 hour time-series
NHEK cells were plated at a density of 8 x 10 000/cm2 and the cell cultures were grown for 24 hours before addition of 2 mM N-Acetyl-L-Cystein. RNA obtained from cultures grown for 1, 12 and 24 hrs after NAC treatment were compared to RNA from untreated cells at the corresponding time points. I.e 1...
ORGANISM(S): Homo sapiens 
2005-07-15 | E-MEXP-146 | biostudies-arrayexpress
TranscriptomicsA Local Regulatory Network Around Three NAC Transcription Factors in Stress Responses and Senescence in Arabidopsis leaves (expression between lines at timepoints).
A network model has been generated that describes the immediate gene expression cascade surrounding three similar but distinct NAC transcription factors that have roles to play in leaf senescence and in many stress responses in Arabidopsis. ANAC019, ANAC055 and ANAC072 belong to the same clade of N...
ORGANISM(S): Arabidopsis thaliana 
2013-04-23 | E-GEOD-45183 | biostudies-arrayexpress
TranscriptomicsA Local Regulatory Network Around Three NAC Transcription Factors in Stress Responses and Senescence in Arabidopsis leaves (Botrytis cinerea infection).
A network model has been generated that describes the immediate gene expression cascade surrounding three similar but distinct NAC transcription factors that have roles to play in leaf senescence and in many stress responses in Arabidopsis. ANAC019, ANAC055 and ANAC072 belong to the same clade of N...
ORGANISM(S): Arabidopsis thaliana 
2013-04-23 | E-GEOD-45594 | biostudies-arrayexpress
TranscriptomicsA Local Regulatory Network Around Three NAC Transcription Factors in Stress Responses and Senescence in Arabidopsis leaves (Dark Induced Senescence).
A network model has been generated that describes the immediate gene expression cascade surrounding three similar but distinct NAC transcription factors that have roles to play in leaf senescence and in many stress responses in Arabidopsis. ANAC019, ANAC055 and ANAC072 belong to the same clade of N...
ORGANISM(S): Arabidopsis thaliana 
2013-04-23 | E-GEOD-45595 | biostudies-arrayexpress
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