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TranscriptomicsThe plasma membrane NADPH oxidase OsRbohA plays a crucial role in developmental regulation and drought-stress response in rice
Plasma membrane NADPH oxidases (NOXs) are major producers of reactive oxygen species (ROS) in plant cells under normal growth and stress conditions. Rice NOXs have multiple homologs but their functional mechanisms are largely unknown. We used microarrays to detail the global gene expression profiles...
ORGANISM(S): Oryza sativa Japonica Group 
2015-12-31 | E-GEOD-54466 | biostudies-arrayexpress
ProteomicsCRK2-mediated control of ROS production by phosphorylation of the RBOHD C-terminus in Arabidopsis
Reactive oxygen species (ROS) are important messengers in eukaryotic organisms. Extracellular ROS production by NADPH oxidases in plants is triggered by receptor-like protein kinase (RLK)-dependent signaling networks. This ROS production is tightly controlled by multiple mechanisms including phospho...
ORGANISM(S): Arabidopsis Thaliana 
2020-03-27 | PXD013525 | panorama
TranscriptomicsGenome-wide analysis of renal gene expression during hyperoxaluria development
Previous studies have proposed that production of reactive oxygen species (ROS) is an important contributor to renal injury and inflammation following exposure to oxalate or calcium-oxalate crystals. The present study was conducted to determine, utilizing global transcriptome analyses, if the NADPH...
ORGANISM(S): Rattus norvegicus 
2012-12-20 | E-GEOD-36446 | biostudies-arrayexpress
ProteomicsSILAC-based quantitative Nox4-Co-immunoprecipitation
Within the family of NADPH oxidases, Nox4 is unique as it is predominantly localized in the endoplasmic reticulum, has constitutive activity and generates H2O2. We hypothesize that these features are consequences of a so far unidentified Nox4-interacting protein. Interacting proteins were screened ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080772 | MassIVE
TranscriptomicsTranscription profiling of Salmonella typhimurium isolated from mice bone marrow derived macrophages with and without NADPH oxidase
NADPH dependent phagocytic oxidase, by producing hydroxyradicals such as hydrogen peroxide, is essential for host defense against Salmonella infection. We used gene array analysis to identify Salmonella enterica serovar Typhimurium genes regulated by NADPH dependent phagocytic oxidase intracellularl...
ORGANISM(S): Salmonella typhimurium 
2007-05-02 | E-MEXP-1089 | biostudies-arrayexpress
GenomicsMycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA
Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA
PRJNA595319 | ENA
ProteomicsAlternative splicing of Arabidopsis G6PD5 can recruits the NADPH-producing OPPP reactions to the endoplasmic reticulum
Glucose-6-phosphate dehydrogenase is the rate-limiting enzyme of the oxidative pentose-phosphate pathway (OPPP). The OPPP mainly provides NADPH and sugar-phosphate building blocks for anabolic pathways and is present in all eukaryotes. In plant cells, the irreversible part of the OPPP is found in se...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2022-07-11 | PXD035221 | JPOST Repository
ProteomicsNADPH Oxidase 1 in Chronic Pancreatitis-Activated Pancreatic Stellate Cells Facilitates the Progression of Pancreatic Cancer
Aims: Patients suffering from chronic pancreatitis (CP) have a higher risk of pancreatic ductal adenocarcinoma (PDAC). NADPH oxidase 1 (Nox1) in activated pancreatic stellate cells from a CP mouse model (CP-activated PaSCs) forms fibrotic tissue and up-regulates matrix metalloproteinase (MMP) 9. Yet...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD034177 | Pride
Nadph oxidase 1  mmp-9  peroxiredoxin  twist1  p38 mapk  pancreatic stellate cells 
ProteomicsEROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling.
The phagocyte NADPH oxidase is critical for host defence, and EROS (Essential for Reactive Oxygen Species) protein is indispensable for expression of its gp91phox-p22phox heterodimer. EROS deficiency in humans is a recently described cause of chronic granulomatous disease (CGD), but its mechanism of...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-30 | PXD025149 | Pride
Nox family Inflammasome Nadph oxidase Ost complex Chaperone T cells P2x receptor Er 
GenomicsNADPH Oxidase 4 and Metabolic Stress in Dahl Salt-Sensitive Rat Kidneys
NADPH Oxidase 4 and Metabolic Stress in Dahl Salt-Sensitive Rat Kidneys
PRJNA1271012 | ENA
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