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Large-scale chromosome structure and spatial nuclear arrangement have been linked to control of gene expression and DNA replication and repair. Genomic techniques based on chromosome conformation capture assess contacts for millions of loci simultaneously, but do so by averaging chromosome conformat...
ORGANISM(S): Mus musculus 
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.
Multiple regulatory elements distant to their targets on the linear genome can influence the expression of a single gene through chromatin looping. Chromosome conformation capture implemented in Hi-C allows for genome-wide agnostic characterization of chromatin contacts. However, detection of functi...
Histone modification profiles in M.Musculus of Kcnq1-imprinted cluster using Nimblegen tiling arrays.
ORGANISM(S): Mus musculus 
Genome organization influences transcriptional regulation by facilitating interactions between gene promoters and distal regulatory elements. To analyse distal promoter contacts we used Capture Hi-C (CHi-C) to enrich for promoter-interactions in HiC libraries from mouse ESC and E14.5 fetal liver. Pl...
ORGANISM(S): Mus musculus 
Proteomic analysis by mass spectrometry was performed to characterize proteins in ascites samples from patients with gastric cancer (N = 7) or liver cirrhosis (N = 3).
ORGANISM(S): Homo Sapiens (human) 
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