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TranscriptomicsTranscription profiling of mouse MC3T3-E1 preosteoblasts with HDIs (trichostatin A, MS-275, or valproic acid) or the vehicle control (DMSO) for 18 hours in osteogenic conditions
Background:; Osteoblast differentiation requires the coordinated stepwise expression of multiple genes. Histone deacetylase inhibitors (HDIs) accelerate the osteoblast differentiation process by blocking the activity of histone deacetylases (HDACs), which alter gene expression by modifying chromati...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9247 | biostudies-arrayexpress
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
ProteomicsProteomics of venom from Trimeresurus malabaricus
This project mainly aims to characterize the complex toxic components present in the venom of Trimeresurus malabaricus (Malabar pit viper). Since Trimeresurus malabaricus (Malabar pit viper) species are mainly inhabited to plantation crop areas, its envenomation is a serious threat to the human popu...
ORGANISM(S): Serpentes 
2020-01-24 | PXD011673 | Pride
Trimeresurus malabaricus Sds-page Malabar pit viper Proteomics Ion-exchange 
ProteomicsPurification of human plasma exosomes for proteomics: optimization and application to detect changes in response to exercise
Extracellular vesicles (EVs) are released into blood from multiple organs and carry molecular cargo that facilitates inter-organ communication and an integrated response to physiological and pathological stimuli. Interrogation of the protein cargo of EVs is currently limited by the absence of optim...
ORGANISM(S): Homo sapiens (Human) 
2021-08-09 | PXD026483 | Pride
Ultracentrifugation High intensity exercise Mass spectrometry Size-exclusion chromatography Bioinformatics 
MetabolomicsHigh-Quality Genome Assembly, Metabolome, Pangenome, and Metabolic Models of Megasphaera hexanoica KCCM 43214T

Megasphaera hexanoica KCCM 43214T, isolated from cow rumen, is capable of producing medium-chain carboxylic acids such as n-caproate and n-caprylate. In this study, we present a high-quality genome assembly, along with intracellular metabolomic profiling and pangenomic an...

2026-04-03 | MTBLS14019 | MetaboLights
TranscriptomicsIllumina Sentrix 6 mouse BeadChip gene expression analysis in mouse spinal cord in the EAE model of Multiple Sclerosis
The study assessed the efficacy of R-flurbiprofen in experimental autoimmune encephalomyelitis (EAE) models of multiple sclerosis in mice. R-flurbiprofen, also known as tarenflurbil, is the R-enantiomer of the cyclooxyygenase inhibitor S-flurbiprofen. It is ineffective in terms of cyclooxygenase inh...
ORGANISM(S): Mus musculus 
2014-08-28 | E-GEOD-60847 | biostudies-arrayexpress
UnknownMajor bioactive phenolics in Bergenia species from the Indian Himalayan region: Method development, validation and quantitative estimation using UHPLC-QqQLIT-MS/MS.
Not available
S-EPMC5531703 | biostudies-literature
UnknownMetabolomics analysis of CEF cells infected with avian leukosis virus subgroup J based on UHPLC-QE-MS.
Not available
S-EPMC11017069 | biostudies-literature
ProteomicsProteomics of Naja naja venom from the Western Ghats of India
This project mainly aims to characterize the complex toxic components present in the venom of Indian cobra (Naja naja) from the Western Ghats of India. Naja naja (NN) is native to the Indian subcontinent and is also found in Pakistan, Sri Lanka, Bangladesh and Southern Nepal. It is a highly venomous...
ORGANISM(S): Serpentes 
2024-06-20 | PXD018936 | Pride
Venom proteomics Western ghats Naja naja 
ProteomicsProteomic profiling of mouse tissues exposed to aircraft noise and particulate matter
The prevalence of non-communicable diseases, particularly cardiovascular disease (CVD), in urbanized and industrialized societies has necessitated intensive investigation into the complex interplay between environmental risk factors and human health. Empirical evidence demonstrates that environmenta...
ORGANISM(S): Mus musculus (Mouse) 
2026-10-15 | PXD070043 | Pride
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