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HeLa cells were treated with Nan-Dyne, a nanchangmycin probe bearing both alkyne and diazirine, irradiated with UV. For competition experiments, cells were also treated with an excess of nanchangmycin. Cells were irradiated with UV, lysed, clicked with azido-biotin, and proteins enriched on neutravi...
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD062176 | Pride
Nanchangmycin exerts antifibrotic activity by inhibiting collagen production, migration, and proliferation of hepatic stellate cells
We report the RNA sequencing results of human primary hepatic stellate cells (HSCs) treated with DMSO or 1 µM nanchangmycin (NCMC) for 48 hours. We find that multiple HSC activity and liver fibrosis related gene signatures, including ECM-related gene signatures, are negatively enriched in nanchangmy...
ORGANISM(S): Homo sapiens 
2022-05-18 | GSE180980 | GEO
Nanchangmycin treated Stapphylococcus aureus Genome sequencing and assembly
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