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ProteomicsProteogenomics of Venturia pirina
This dataset relates to a proteogenomic analysis for Venturia pirina, a fungus that causes scab disease on European pear (Pyrus communis). V. pirina is host specific and infection is thought to be mediated by small, secreted effector proteins. To focus on these effectors we analysed extracts from V....
ORGANISM(S): Venturia pirina 
2014-07-02 | PXD000710 | Pride
Lc-msms Ave1 Proteogenomics Effectors Venturia pirina 
ProteomicsProximity labelling and SILAC based proteomic approach identifies proteins at the interface of homotypic and heterotypic cancer cell interactions.
Cell-cell interactions are critical for the growth of organisms and maintaining homeostasis. In the tumor microenvironment, these interactions promote cancer progression. Given their importance in healthy and diseased conditions, we have developed a method to analyze the cell-to-cell interactome. Ou...
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD052917 | Pride
Silac based  proteomics Nano lc-ms/ms orbitap Cell-cell interactions 
ProteomicsProximity labelling and SILAC based proteomic approach identifies proteins at the interface of homotypic and heterotypic cancer cell interactions.
Cell-cell interactions are critical for the growth of organisms and maintaining homeostasis. In the tumor microenvironment, these interactions promote cancer progression. Given their importance in healthy and diseased conditions, we have developed a method to analyze the cell-to-cell interactome. Ou...
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD060134 | Pride
Silac based  proteomics Nano lc-ms/ms orbitap Cell-cell interactions 
ProteomicsLineage-specific oncogenes drive growth of major forms of human cancer using common downstream mechanisms
Aim of the experiment was to identify changes in protein-protein interactions between proliferating and non-proliferating cells. For this purpose, RKO cells were treated with 20nM Trametinib, HCT116 with 8nM Trametinib, and NCI-H1975 100nM Osimertinib. At these concentrations, the wild type cell lin...
ORGANISM(S): Homo sapiens (Human) 
2025-07-17 | PXD037155 | Pride
Proteomics Pisa assay Protein solubility Lung cancer Proliferation Lc-ms/ms Colorectal cancer 
ProteomicsTHE INTRA-MITOCHONDRIAL O-GLCNACYLATION SYSTEM ACUTELY REGULATES OXPHOS CAPACITY AND ROS DYNAMICS IN THE HEART
O-linked N-acetylglucosamination (O-GlcNAcylation) of proteins is increasingly recognized as an important cellular regulatory mechanism. In the heart, nucleocytoplasmic O-GlcNAcylation is involved in the modulation of multiple pathophysiological processes. However, the mechanisms leading to O-GlcNAc...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-11 | PXD026495 | Pride
Oxidative phosphorylation Mitochondria O-glcnac Heart 
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