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GenomicsChromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants (ChIP-seq)
Chromatin-based functional genomic analyses and genomewide association studies (GWASs) together implicate enhancers as critical elements influencing gene expression and risk for common diseases. Here, we performed systematic chromatin and transcriptome pro- filing in human pancreatic islets. Integra...
ORGANISM(S): Homo sapiens 
2013-11-08 | E-GEOD-51311 | biostudies-arrayexpress
TranscriptomicsChromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants (RNA-seq)
Chromatin-based functional genomic analyses and genomewide association studies (GWASs) together implicate enhancers as critical elements influencing gene expression and risk for common diseases. Here, we performed systematic chromatin and transcriptome profiling in human pancreatic islets. Integrate...
ORGANISM(S): Homo sapiens 
2013-11-08 | E-GEOD-51310 | biostudies-arrayexpress
UnknownA Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX.
Not available
S-EPMC3608171 | biostudies-literature
UnknownSingle-cell transcriptomics from human pancreatic islets: sample preparation matters.
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S-EPMC6964677 | biostudies-literature
UnknownAnalysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
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S-EPMC6826141 | biostudies-literature
UnknownSingle-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours.
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S-EPMC10274787 | biostudies-literature
UnknownPutative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites.
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S-EPMC4715509 | biostudies-literature
UnknownHuman pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.
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S-EPMC9963967 | biostudies-literature
UnknownA Transcription Start Site Map in Human Pancreatic Islets Reveals Functional Regulatory Signatures.
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S-EPMC8336006 | biostudies-literature
UnknownSingle-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures.
Not available
S-EPMC6961712 | biostudies-literature
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