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MetabolomicsThe nasal microbiome and metabolites are altered in depression patients
Depressive disorder is a heterogeneous neuropsychiatric disorder. It affects millions of people worldwide. The exact causes of depressive behavior remain unclear and are believed to implicate both genetic and environmental factors. In the past decade, there have been numerous studies on the dysbiosi...
2025-07-21 | MTBLS10742 | MetaboLights
MetabolomicsCharacterization of the nasal microbiome and metabolome in children with Henoch-Schonlein purpura and children with Henoch-Schonlein purpura nephritis

Three groups of eligible subjects were included, including 20 cases in the HSP group, 20 cases in the HSPN group, and 20 cases in the healthy control (HC) group. Nasal lavage samples from each group were subjected to 16SrRNA gene sequencing and metabolomic analyses to screen differential flora an...

2026-04-11 | MTBLS12590 | MetaboLights
MetabolomicsCholic Acid as a Potential Mediator in PD Olfactory Dysfunction: Insights from Nasal Microbiome-Metabolite Interactions Research

Background: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by both motor and non-motor symptoms, including olfactory dysfunction, which often precedes motor symptoms by several years. However, the underlying mechanisms linking olfactory dysfunction in PD to bio...

2025-07-07 | MTBLS12692 | MetaboLights
MetabolomicsCharacterizing the nasal metabolome and exposome by LC-HRMS: Opportunities and challenges

The nasal cavity represents a host-microbial interface critical to respiratory defense against viral infections, including those caused by influenza virus, respiratory syncytial virus, rhinovirus or SARS-CoV-2. Although the nasal microbiome itself has been well characterized, the nasal metabolome...

2026-10-22 | MTBLS14409 | MetaboLights
ProteomicsIn-depth proteomic analysis of nasal fluids from patients with chronic rhinosinusitis and nasal polyps by data-independent acqusition
Antibiotics are commonly prescribed to treat chronic rhinosinusitis (CRS). However, the effects of antibiotics on the microbiome and secreted proteome remain unknown in regard to CRS.We analyzed the effects of antibiotics on the nasal secreted proteome inthe context of CRS using data-independent acq...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018960 | Pride
Human Crs Nasal fluids Data independent acqusition 
GenomicsNasal microbiome
Nasal sampling methods for the Microbiome: What is out there to find out what is in there
PRJNA924545 | ENA
Genomicsnasal microbiome
nasal microbiome Metagenome
PRJNA488874 | ENA
ProteomicsNasal microbiome - syncom screening
Non-targeted metabolomics data for 20 synthetic communities resembling the nasal microbiome.
ORGANISM(S): Synthetic Community 
2025-01-04 | MSV000096776 | MassIVE
MetabolomicsResearch on the microbiota and metabolic characteristics of type 2 chronic rhinosinusitis based on the analysis of 16S amplicon sequencing combined with metabolomics

Objective:

To investigate the diversity of nasal microbiota and metabolic characteristics of patients with Type 

2 chronic rhinosinusitis, as well as the interactions and potential regulatory relationships between 

the nasal microbiota and their metabolites by conducti...

2025-10-21 | MTBLS13192 | MetaboLights
GenomicsNasal Microbiome Synthetic communities
Synthetic bacterial communties associated with the human nasal microbiome
PRJNA1370791 | ENA
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