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ProteomicsMouse Th17 T cells, IL-23 stimulated
Interleukin 23 (IL-23) triggers pathogenic features in pro-inflammatory, IL-17-secreting T cells (Th17 and Tγδ17) that play a key role in the development of inflammatory diseases. However, the IL-23 signaling cascade remains largely undefined. Here we used quantitative phosphoproteomics to character...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-25 | PXD016633 | Pride
Th17 Mouse T lymphocyte Il-23 
TranscriptomicsRole of PKD2 in TCR-induced transcriptional reprogramming of naïve T cells
Comparison of transcriptional profile of TCR stimulated P14-TCR wild-type and P14-PKD2 null murine lymph node cells Lymph node cells from 3 biological replicates (3 wild-type and 3 PKD2 null mice) were isolated and left unstimulated or stimulated for 4 hours with antigenic peptide (gp33-41) prior to...
ORGANISM(S): Mus musculus 
2012-02-29 | E-GEOD-33942 | biostudies-arrayexpress
TranscriptomicsExpression data from P14 TCR cytotoxic T cells overexpressing HDAC7 phosphorylation deficient mutant
The present study reports an unbiased analysis of the cytotoxic T cell serine-threonine phosphoproteome using high resolution mass spectrometry. Approximately 2,000 phosphorylations were identified in CTLs of which approximately 450 were controlled by TCR signaling. A significantly overrepresented g...
ORGANISM(S): Mus musculus 
2011-03-13 | E-GEOD-27092 | biostudies-arrayexpress
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