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Reference materials are vital to benchmarking the reproducibility of clinical tests and essential for monitoring laboratory performance for clinical proteomics. The reference material utilized for mass spectrometric analysis of the human proteome would ideally contain enough proteins to be suitably ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-14 | PXD008952 | Pride
Reference materials are vital to benchmarking the reproducibility of clinical tests and essential for monitoring laboratory performance for clinical proteomics. The reference material utilized for mass spectrometric analysis of the human proteome would ideally contain enough proteins to be suitably ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2021-12-08 | MSV000088547 | MassIVE
RNA-seq analysis of HuH-7, NCI-H1299 and HEK-293T cells
Protein characterization of cancer proteins is vital for advancing cancer research, serving as foundational resources in integrative multi-omics studies. Recently, significant progress has been made in expanding the mass spectrometry-based proteomics and detecting cancer proteins with a particular f...
ORGANISM(S): Homo sapiens (Human) 
2026-05-01 | PXD071155 | Pride
The diversity and complexity of the cancer transcriptome hold the potential to yield tumor-specific transcripts (TSTs) in cancer. We report a novel LIN28B variant, LIN28B-TST, which is specifically expressed in hepatocellular carcinoma (HCC) and many other cancer types. LIN28B-TST initiates from a d...
ORGANISM(S): Homo sapiens 
2018-01-24 | GSE109528 | GEO
Genomics
Transcriptome analysis of BN-7 treated NCI-H460 and A549 lung cancer cell lines by RNA sequencing
While the roles of individual nuclear receptor (NR) in human diseases have been well characterized, interplays among NRs have not been extensively characterized due, in part, to technical difficulties in simultaneously monitoring molecular activities of all 48 NR genes. Using systems-level analysis ...
ORGANISM(S): Homo sapiens 
2011-12-22 | GSE18431 | GEO
The receptor tyrosine kinase (RTK) EGFR is overexpressed and mutated in NSCLC. These mutations can be targeted by RTK inhibitors (TKIs), such as erlotinib. Chromatin-modifying agents offer a novel therapy approach by sensitizing tumor cells to TKIs. The NSCLC cell lines HCC827 (EGFR mutant, adenocar...
ORGANISM(S): Homo sapiens 
Oncolytic viral therapy represents an alternative therapeutic strategy for the treatment of cancer. This therapy relies on efficient replication of virus in tumor cells in vivo with minimal or no replication in normal tissues. We recently described GLV-1h68 as a modified Vaccinia Virus (VACV) constr...
ORGANISM(S): Homo sapiens 
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