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ProteomicsHuma Multiple Myeloma Cell line, AMO1, treated with NCP26, LC-MSMS analysis
The human multiple myeloma cell line, AMO1, was treated with NCP26, an ATP-competitive EPRS inhibitor, and a total proteome-wide analysis was performed to determine the effect of NCP26 treatment on protein dynamics.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD029453 | Pride
Lc-msms Huma Ncp26 Multiple myeloma Cell line Tmt-labeling Amo1 
GenomicsNCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma. Bulk RNA-seq data.
NCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma. Bulk RNA-seq data.
PRJNA773804 | ENA
TranscriptomicsNCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma. Bulk RNA-seq data.
Glutamyl-prolyl-tRNA synthetase (EPRS) is a unique bifunctional aminoacyl-tRNA synthetase which catalyzes the ATP-dependent aminoacylation of glutamyl and prolyl residues to cognate tRNAs, constituting fundamental building blocks in protein synthesis. Genomic data suggest that EPRS promotes disease ...
ORGANISM(S): Homo sapiens 
2022-09-08 | GSE186445 | GEO
TranscriptomicsNCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma. Single-cell RNA-seq data BM samples.
Glutamyl-prolyl-tRNA synthetase (EPRS) is a unique bifunctional aminoacyl-tRNA synthetase which catalyzes the ATP-dependent aminoacylation of glutamyl and prolyl residues to cognate tRNAs, constituting fundamental building blocks in protein synthesis. Genomic data suggest that EPRS promotes disease ...
ORGANISM(S): Homo sapiens 
2022-09-08 | GSE186447 | GEO
GenomicsNCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma. Single-cell RNA-seq data BM samples.
NCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma. Single-cell RNA-seq data BM samples.
PRJNA773807 | ENA
GenomicsNCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma
NCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma
PRJNA773806 | ENA
UnknownProlyl-tRNA synthetase as a novel therapeutic target in multiple myeloma.
Not available
S-EPMC9834298 | biostudies-literature
TranscriptomicsNCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma
This SuperSeries is composed of the SubSeries listed below.
ORGANISM(S): Homo sapiens 
2022-09-08 | GSE186448 | GEO
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