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ProteomicsHuma Multiple Myeloma Cell line, AMO1, treated with NCP26, LC-MSMS analysis
The human multiple myeloma cell line, AMO1, was treated with NCP26, an ATP-competitive EPRS inhibitor, and a total proteome-wide analysis was performed to determine the effect of NCP26 treatment on protein dynamics.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD029453 | Pride
Lc-msms Huma Ncp26 Multiple myeloma Cell line Tmt-labeling Amo1 
ProteomicsDifferential protein expression between Carfilzomib-sensitive (AMO1) and resistant (AMO1-CFZ) multiple myeloma cells
Carfilzomib-sensitive (AMO1) and resistant (AMO1-CFZ) MM cells were grown in RPMI-1640 medium supplemented with 10 % FBS and 0.68 mM L-glutamine, in a humidified incubator at 5% CO2 and 37 °C. The AMO1-CFZ medium was additionally added 90 nM CFZ, while the CFZ sensitive AMO1 cells were added vehicle...
ORGANISM(S): Homo sapiens (Human) 
2024-06-07 | PXD045439 | Pride
Myeloma 
UnknownThe barley amo1 locus is tightly linked to the starch synthase IIIa gene and negatively regulates expression of granule-bound starch synthetic genes.
Not available
S-EPMC3193023 | biostudies-literature
TranscriptomicsHierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness
Comparison of the TP53 wild-type myeloma cell line AMO1 with the CRISPR/Cas9 engineered AMO1 cell line named UMC901. UMC901 harbors bi-allelic alterations to TP53: TP53 del/mut. Analysis of impact of TP53 alterations on gene transcription and identification of affected pathways by transcriptome-wide...
ORGANISM(S): Homo sapiens 
2019-08-06 | GSE132340 | GEO
TranscriptomicsNEAT1-driven ceRNA network in multiple myeloma
The lncRNA NEAT1 is overexpressed in multiple myeloma (MM) plasma cells and plays a key role in MM pathogenesis. NEAT1 is involved in ceRNA network in several cancers; however, data in MM are virtually absent. This study identified a NEAT1-driven ceRNA network involving 96 miRNAs and 40 target genes...
ORGANISM(S): Homo sapiens 
2026-04-15 | GSE304590 | GEO
TranscriptomicsEffect of overexpression of PHF19 in multiple myeloma cells [RNA-seq]
To investigate the transcriptomic effect of PHF19 overexpression in MM cells. We then performed gene expression profiling analysis using data obtained from RNA-seq of AMO1 cells with differential PHF19 expression.
ORGANISM(S): Homo sapiens 
2023-01-31 | GSE224200 | GEO
UnknownPositioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance.
Not available
S-EPMC7102895 | biostudies-literature
UnknownCynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma.
Not available
S-EPMC10618500 | biostudies-literature
UnknownGenetic redundancy in the catabolism of methylated amines in the yeast Scheffersomyces stipitis.
Not available
S-EPMC5816127 | biostudies-literature
UnknownBortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells.
Not available
S-EPMC3587640 | biostudies-literature
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