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Transcriptomics5' Cap-Isolated RNA Pol II Transcripts and ENCODE Tiling Arrays to Identify Gene Expression Changes in Hepatitis C Liver
Recent studies of the human transcriptome suggest that many transcripts have short or lack 3' poly(A) ends. In addition, the length of 3' poly(A) ends may vary for some transcript to regulate mRNA translation. Heterogeneous lengths of poly(A) ends may introduce variations in measuring RNA transcript...
ORGANISM(S): Homo sapiens 
2011-03-29 | E-GEOD-18904 | biostudies-arrayexpress
ProteomicsProteomic analysis of Fusarium sp. DS 682 Fungal Mineral Weathering in a Mineral Doped Soil Micromodel
Cell lysates of Fusarium sp. DS 682, a saprotrophic fungus, were prepared from fungal biomass grown on PDA agar without M9 and micronutrients. Fungus was exposed to minerals, 100 uL of 50% (w/v) natural kaolinite solution. Three fungal plate collections for each growth condition, with (+ mineral) an...
ORGANISM(S): Fusarium Sp. (ncbitaxon:29916) 
2021-04-16 | MSV000087221 | MassIVE
ProteomicsThe Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation: siEYA4 pY IP-MS
The Eyes Absent family of proteins (EYA1-4) are a biochemically unique group of tyrosine phosphatases known to be tumour promoting across a range of cancer types. To date, the molecular targets of EYA phosphatase activity remain largely uncharacterised. Here, we identify Polo-like kinase 1 (PLK1) as...
ORGANISM(S): Homo sapiens (Human) 
2024-02-26 | PXD036430 | Pride
Py ip Eya4 
ProteomicsThe Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation: EYA4 BioID
The aim of this project was to identify the EYA4 interactome. This was part of a larger research goal of identifying EYA4 phosphatase substrates and the cell biological consequences of their dephosphorylation.
ORGANISM(S): Homo sapiens (Human) 
2024-02-26 | PXD036405 | Pride
Eya4 Bioid 
ProteomicsAnalysis of ZNF827 Halotag pulldown for a manuscript titled ‘ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway’
Mass spectrometry analysis of ZNF827 Halotag pulldown ZNF827 pull-downs were performed in HEK 293T cells overexpressing HaloTag ZNF827 or empty vector control using the HaloTag® Protein Pull-Down and Labelling System (Promega) according to the manufacturer’s protocol. Pull-downs were subjected mass ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-23 | PXD050191 | Pride
Atr Ssdna Znf827 Dna damage response 
TranscriptomicsGene expression patterns in peripheral blood correlate with the extent of coronary artery disease
Gene expression profile in circulating leukocytes identifies patients with coronary artery disease Peter Sinnaeve, Mark Donahue, Peter Grass, Jacky Vonderscher, David Seo, Pascal Goldschmidt, Christopher Granger Department of Medicine, Duke University, Durham, NC, USA, Novartis Institute for Biome...
ORGANISM(S): Homo sapiens 
2008-10-31 | E-GEOD-12288 | biostudies-arrayexpress
TranscriptomicsInterferon signaling during early experimental malaria infection
Microarray profiling of whole blood of immunodeficient mouse strains at 24h after infection with Plasmodium chabaudi. Multiple independent replicates collected for each knockout. RNA isolated and amplified. Hybridized as two-color experiment against a common pooled reference.
ORGANISM(S): Mus musculus 
2012-11-19 | E-GEOD-23565 | biostudies-arrayexpress
TranscriptomicsBartonella quintana: growth phase and temperature response
Transcriptional profiling of Bartonella quintana grown on a plate at 28C and 37C for various time points. Comparing each individual sample in cy5 to a pooled mix of all samples in cy3 to preserve a common denominator.
ORGANISM(S): Bartonella quintana 
2012-12-05 | E-GEOD-42685 | biostudies-arrayexpress
TranscriptomicsTMPRSS2 Influences Prostate Cancer Metastasis
TMPRSS2 is an androgen-regulated cell surface serine protease expressed predominantly in prostate epithelium. TMPRSS2 is expressed highly in localized high-grade prostate cancers and in the majority of human prostate cancer metastasis. Through the generation of mouse models with a targeted deletion ...
ORGANISM(S): Mus musculus 
2014-09-09 | E-GEOD-58822 | biostudies-arrayexpress
UnknownPiglet immunization with a spike subunit vaccine enhances disease by porcine epidemic diarrhea virus.
Not available
S-EPMC7851141 | biostudies-literature
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