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ProteomicsAnalysis of ZNF827 Halotag pulldown for a manuscript titled ‘ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway’
Mass spectrometry analysis of ZNF827 Halotag pulldown ZNF827 pull-downs were performed in HEK 293T cells overexpressing HaloTag ZNF827 or empty vector control using the HaloTag® Protein Pull-Down and Labelling System (Promega) according to the manufacturer’s protocol. Pull-downs were subjected mass ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-23 | PXD050191 | Pride
Atr Ssdna Znf827 Dna damage response 
TranscriptomicsZNF827-dependent splicing dynamics are critical for EMT during development and disease [RNA-seq]
Epithelial to mesenchymal transition (EMT) is a multi-step process during which epithelial cells become mesenchymal stem cells. EMT is involved during embryonic development, wound healing, fibrosis and tumor metastasis. Here we show that ZNF827, a C2H2-zinc finger containing protein, is critical for...
ORGANISM(S): Homo sapiens 
2023-02-14 | GSE99720 | GEO
UnknownZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway.
Not available
S-EPMC10933417 | biostudies-literature
GenomicsHomo sapiens
ZNF827-dependent splicing dynamics are critical for EMT during development and disease [ChIP-seq]
PRJNA389428 | ENA
GenomicsHomo sapiens
ZNF827-dependent splicing dynamics are critical for EMT during development and disease [RNA-seq]
PRJNA389427 | ENA
ProteomicsA complex epigenome-splicing crosstalk governs epithelial to mesenchymal transition in metastasis and brain development
Epithelial to Mesenchymal Transition (EMT) renders epithelial cells to acquire migratory characteristics during development and cancer metastasis. While epigenetic and splicing changes have been implicated in EMT, the mechanisms governing their crosstalk remain poorly understood. Here, we identify ...
ORGANISM(S): Homo sapiens (Human) 
2022-06-21 | PXD034511 | Pride
Emt 
GenomicsZNF827-dependent splicing dynamics are critical for EMT during development and disease
ZNF827-dependent splicing dynamics are critical for EMT during development and disease
PRJNA389409 | ENA
TranscriptomicsA complex epigenome-splicing crosstalk governs epithelial to mesenchymal transition in metastasis and brain development
Epithelial to Mesenchymal Transition (EMT) renders epithelial cells migratory properties. While epigenetic and splicing changes have been implicated in EMT, the mechanisms governing their crosstalk remain poorly understood. Here, we discovered a C2H2 zinc finger protein, ZNF827, is strongly induced ...
ORGANISM(S): Homo sapiens 
2022-05-31 | GSE173874 | GEO
TranscriptomicsZNF827-dependent splicing dynamics are critical for EMT during development and disease
This SuperSeries is composed of the SubSeries listed below.
ORGANISM(S): Homo sapiens 
2023-02-14 | GSE99722 | GEO
GenomicsA complex epigenome-splicing crosstalk governs epithelial to mesenchymal transition in metastasis and brain development
A complex epigenome-splicing crosstalk governs epithelial to mesenchymal transition in metastasis and brain development
PRJNA727336 | ENA
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