Neoangiogenesis

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CHEBI:48929 (2)
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CHEBI:36315 (2)
CHEBI:68434 (2)

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Isocitric lactone (2)
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1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0)* (2)
1-linoleoyl-2-arachidonoyl-GPC (18:2/20:4n6)* (2)
1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6)* (2)
1-oleoyl-2-linoleoyl-GPE (18:1/18:2)* (2)
1-(1-enyl-palmitoyl)-2-linoleoyl-GPE (P-16:0/18:2)* (2)

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Study type

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Lab affiliation

Institute of Biomedical Chemistry, "Human Proteome" Core Facility Centre (1)
University of Eastern Piedmont Department of Sciences and Technological Innovation, University of Piemonte Orientale, Italy (1)

Location

France (2)

Keyword

Bevacizumab (1)

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Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth

The vasculature represents a highly plastic compartment, capable of switching from a quiescent to an active proliferative state during angiogenesis. Metabolic reprogramming in endothelial cells (ECs) thereby is crucial to cover the increasing cellular energy demand under growth conditions. Here w...

2020-06-29 | MTBLS1764 | MetaboLights

RUNX2 stimulates neoangiogenesis through the RUNT domain in melanoma

Transcription factors, by acting on gene expression can affect molecular pathways and can thereby induce malignant transformation. Among the transcription factors involved in cellular transformation, we recently highlighted the role of RUNX2 in melanoma cell migration and proliferation. In the prese...

ORGANISM(S): Homo sapiens (Human)

2019-11-13 | PXD012096 | Pride