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UnknownProspective multicentre randomized double-blind placebo-controlled parallel group study on the efficacy and tolerability of StroVac® in patients with recurrent symptomatic uncomplicated bacterial urinary tract infections.
Not available
S-EPMC9870822 | biostudies-literature
GenomicsChIP-Seq reveals regulation of the heterochromatic mark, H3K9me3, in NAc following repeated cocaine administration
Repeated administration of the psychostimulant cocaine has been shown to produce persistent alterations in genome-wide transcriptional regulatory networks, chromatin remodeling activity and, ultimately, gene expression profiles in the brain’s reward circuitry. Virtually all previous investigations h...
ORGANISM(S): Mus musculus 
2011-01-18 | E-GEOD-24850 | biostudies-arrayexpress
UnknownInitial surgical management of injuries to the urogenital tract in patients with polytrauma and/or severe injuries: a systematic review and clinical practice guideline update.
Not available
S-EPMC12037646 | biostudies-literature
GenomicsBAZ1B in Nucleus Accumbens Regulates Reward-Related Behaviors in Response to Distinct Emotional Stimuli
ATP-dependent chromatin remodeling proteins are being implicated increasingly in the regulation of complex behaviors, including models of several psychiatric disorders. Here, we demonstrate that Baz1b, an accessory subunit of the ISWI family of chromatin remodeling complexes, is upregulated in the n...
ORGANISM(S): Mus musculus 
2016-07-30 | E-GEOD-85005 | biostudies-arrayexpress
UnknownDivergent effects of a combined hormonal oral contraceptive on insulin sensitivity in lean versus obese women.
Not available
S-EPMC3143285 | biostudies-literature
GenomicsHistone Arginine Methylation in Cocaine Action: Essential Role of Src Signaling in the Nucleus Accumbens
Despite addiction being one of the most prevalent and debilitating disorders worldwide, effective treatments are lacking. Repeated cocaine exposure induces maladaptive transcriptional regulation within the brainâ??s reward circuitry, such as the nucleus accumbens (NAc), and epigenetic mechanisms, su...
ORGANISM(S): Mus musculus 
2016-08-08 | E-GEOD-85310 | biostudies-arrayexpress
GenomicsEssential role of poly(ADP-ribosyl)ation in cocaine action
Many of the long-term effects of cocaine on the brain's reward circuitry have been shown to be mediated by alterations in gene expression. Several chromatin modifications, including histone acetylation and methylation, have been implicated in this regulation, but the effect of other histone modifica...
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-55136 | biostudies-arrayexpress
UnknownQuantitative MRI detects delayed perfusion and impact of bronchial artery dilatation on pulmonary circulation in patients with cystic fibrosis.
Not available
S-EPMC12417259 | biostudies-literature
UnknownInsulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with polycystic ovary syndrome.
Not available
S-EPMC2574418 | biostudies-literature
Genomicsb-Catenin Mediates the Development of Behavioral Resilience [ChIP-Seq]
Here we show that ?-catenin mediates pro-resilient and anxiolytic effects in mice in the nucleus accumbens (NAc), a key brain reward region, an effect that is mediated by ?-catenin signaling in D2-type medium spiny neurons (MSNs) specifically. Conversely, blocking ?-catenin function in NAc promotes...
ORGANISM(S): Mus musculus 
2014-11-13 | E-GEOD-61294 | biostudies-arrayexpress
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