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To investigate the dynamic changes of prostate cancer cells during neuroendocrine transdifferentiation (NEtD), we performed single-cell RNA sequencing (scRNA-seq) on longtitudinal LTL331 PDX model derived from patient samples. Analysis of the data depicts a comprehensive cellular and molecular lands...
ORGANISM(S): Homo sapiens 
2026-09-30 | GSE297328 | GEO
Prostate tumors contain foci of neuroendocrine transdifferentiation (NETD), resulting in an increase of androgen-independent neuroendocrine-like (NE) tumor cells, whose number significantly correlates with tumor aggressiveness and a lower survival rate. The mechanisms leading to NETD and the exact r...
ORGANISM(S): synthetic construct Homo sapiens 
2018-07-19 | GSE105416 | GEO
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