Neuraminidase 1

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Lab affiliation

National Heart and Lung Institute, Imperial College London, London, UK (3)
Copenhagen Center for Glycomics, University of Copenhagen (2)
School of Chemistry and Biochemistry and the Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332, USA (2)
Associate Professor Glyco MS Group Copenhagen Center for Glycomics (CCG) Department of Cellular and Molecular Medicine University of Copenahgen Blegdamsvej 3 2200 Copenhagen N Denmark (1)
Beth Israel Deaconess Medical Center, Department of Surgery National Center for Functional Glycomics Harvard Medical School Boston, MA, 02215, U.S.A. (1)
Biomolecular Measurement Division, National Institute of Standards and Technology (1)
Boston University School of Medicine (1)
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Centre for Biologics Evaluation, Biologics and Genetic Therapies Directorate, Health Canada, Canada (1)
College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, China (1)
Copenhagen Center for Glycomics (CCG), Glyco-MS Group Department of Cellular and Molecular Medicine University of Copenhagen (1)
Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen (1)
Copenhagen Center for Glycomics, University of Copenhagen, Denmark (1)
Core Facility for Omics Sciences, IRCCS Istituto Giannina Gaslini, Genoa, Italy (1)
Department of Biochemistry Center for Biomedical Mass Spectrometry Boston University School of Medicine (1)
Department of Cellular and Molecular Medicine, University of Copenhagen (1)
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. (1)
Department of Psychiatry, Oregon Health & Science University, Portland, OR (1)
Department of Virology III, National Institute of Infectious Diseases (1)
Experimental Pathology and Therapeutics Group, IPO Porto Research Center (CI-IPOP), Portuguese Oncology Institute (IPO Porto), 4200-072 Porto, Portugal (1)
Experimental Pathology and Therapeutics Group, Portuguese Institute of Oncology, Porto, Portugal (1)
Glyco MS Group Copenhagen Center for Glycomics (CCG) Department of Cellular and Molecular Medicine University of Copenhagen (1)
Health Canada (1)
Institute of Molecular Medicine and Cell Research, University of Freiburg, Stefan Meier Strasse 17, 79104, Freiburg, Germany (1)
King's British Heart Foundation Centre, King's College London, London, UK (1)
King's College London (1)
Microbiology department at the Icahn School of Medicine atMount Sinai (1)
Nanjing University of Chinese Medicine and China Pharmaceutical University (1)
National Heart and Lung Institute, Imperial College London, United Kingdom (1)

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Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption

Sialidosis is an ultrarare multisystemic lysosomal disease caused by mutations in the neuraminidase 1 (NEU1) gene. The severe Type II form of the disease, manifests with a prenatal/infantile or juvenile onset, bone abnormalities, severe neuropathology and visceromegaly. A subset of these patients pr...

ORGANISM(S): Mus musculus (Mouse)

2024-01-26 | PXD044833 | Pride

Seryl-leucine core 1 O-glycosylated peptide (SLC1G) identification

Not available

ORGANISM(S): Homo sapiens

ST001104 | MetabolomicsWorkbench

Transport of influenza A virus neuraminidase to host cell surface and virus replication are regulated by ARHGAP21 and Cdc42

Influenza virus neuraminidase (NA), a type II transmembrane glycoprotein, is transported to the virus assembly site at the plasma membrane and is a major viral envelope component that plays a critical role in the release of progeny virions and in determination of host range restriction. Although sig...

ORGANISM(S): Homo sapiens

2012-04-03 | E-GEOD-32878 | biostudies-arrayexpress

Targeting Neuraminidase 4 Attenuates Kidney Fibrosis in Mice

Despite significant progress in therapy, there remains a lack of substantial evidence regarding the molecular factors that lead to renal fibrosis. Neuraminidase 4 (NEU4) is an enzyme that removes sialic acids from glycoconjugates, while the function of NEU4 in chronic progressive fibrosis has not be...

ORGANISM(S): Homo sapiens (Human)

2025-05-06 | PXD051726 | Pride

4ʹ-heptamethoxyflavone Neu4 3 5 6 3ʹ Yap 7 8 Renal fibrosis

Neuraminidase-1 promotes heart failure after ischemia/reperfusion injury by affecting cardiomyocytes and invading monocytes/macrophages.

Not available

S-EPMC7519006 | biostudies-literature

Targeting Human Parainfluenza Virus Type-1 Haemagglutinin-Neuraminidase with Mechanism-Based Inhibitors.

Not available

S-EPMC6563277 | biostudies-literature

Neuraminidase 1 promotes renal fibrosis development in male mice.

Not available

S-EPMC10043283 | biostudies-literature