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TranscriptomicsMultinucleated Tartrate Resistant Acid Phosphatase Positive Cells with Macrophage and Osteoclast Phenotypes in Bone
Prothrombin (PT) and osteopontin (OPN) promotes adhesion of different TRAP-positive multinucleated cells isolated from rat long bone (Hu et al. Exp Cell Res. 2008; 314: 638-50). The PT-adhering cell could represent either an immature precursor to the OPN-adherent osteoclast or constitute a distinct...
ORGANISM(S): Rattus norvegicus 
2010-12-31 | E-GEOD-19950 | biostudies-arrayexpress
TranscriptomicsGeneration and purification of Th1 and Th2 effector and memory CD4+ T cells
Naïve CD4+ T cells were isolated from spleen of AND TcR transgenic/green fluorescence protein (GFP) transgenic mice (Kaye et al., Nature 1989;341:746, Wright et al, Blood 2001;97:2278) that recognize a peptide of pigeon cytochrome C in the context of I-Ek and express CD44lo, CD62Lhi, CD45RBhi, and ...
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-8352 | biostudies-arrayexpress
TranscriptomicsIllumina Sentrix 6 mouse BeadChip gene expression analysis in mouse spinal cord in the EAE model of Multiple Sclerosis
The study assessed the efficacy of R-flurbiprofen in experimental autoimmune encephalomyelitis (EAE) models of multiple sclerosis in mice. R-flurbiprofen, also known as tarenflurbil, is the R-enantiomer of the cyclooxyygenase inhibitor S-flurbiprofen. It is ineffective in terms of cyclooxygenase inh...
ORGANISM(S): Mus musculus 
2014-08-28 | E-GEOD-60847 | biostudies-arrayexpress
ProteomicsImpact of Age and Sex on Plasma Proteome Changes in Mice upon Radiation Exposure
The aim of this project is to assess the impact that age and sex have as parameters for biomarker discovery in radiation research using high-throughput proteomics.
ORGANISM(S): Mus musculus (Mouse) 
2022-05-10 | PXD015859 | Pride
Plasma Radiation Mus musculus Tmt Sex Tandem-mass tag Mouse Age Orbitrap fusion 
TranscriptomicsTranscriptomic effects of prenatal exposure to corticosteroids on synaptic transmission
Prenatal exposure to synthetic corticosteroids can significantly alter postnatal development through changes in neurotransmitters and their receptors, and thus having long-lasting behavioral effects. Some of these changes have been observed in animal experiments, others also in humans prenatally exp...
ORGANISM(S): Rattus norvegicus 
2016-01-09 | E-GEOD-76694 | biostudies-arrayexpress
UnknownQuick and Easy Screening for Vitamin D Insufficiency in Adults: A Scoring System to Be Implemented in Daily Clinical Practice.
Not available
S-EPMC4998626 | biostudies-literature
UnknownLC-MS/MS-based quantification of tryptophan, kynurenine, and kynurenic acid in human placental, fetal membranes, and umbilical cord samples.
Not available
S-EPMC10397233 | biostudies-literature
TranscriptomicsGene expression data for two xenograft models representing luminal-like and basal-like breast cancer
Choline (reference 1) and glucose (reference 2) was studied using HR MAS MR spectroscopy data and 105 and 38 gene transcripts were selected respectively from the microarray data to study differences between two xenograft models. Reference 1: Moestue SA et al, Distinct choline metabolic profiles are ...
ORGANISM(S): Homo sapiens 
2010-12-08 | E-GEOD-25915 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Molecular Signature of Cholangiocarcinoma and Its Trandifferentation-Related Genes
Cholangiocarcinoma (CC) is an aggressive tumor that shows a poor survival rate even after resection. The present study aimed at identification of the genome-wide expressed genes related to CC oncogenesis and its sarcomatous transdifferentiation using DNA microarray technology. The differentially exp...
ORGANISM(S): Homo sapiens 
2014-02-07 | E-GEOD-22633 | biostudies-arrayexpress
TranscriptomicsEB-mediated NPY expression and release.
Neuropeptide Y (NPY) is an endogenous modulator of neuronal activity by regulating GABA and glutamate release. Previously, we found that estradiol modulates NPY expression in the hippocampal dentate gyrus. Here we investigated which estrogen receptor type activation is required for the NPY expressio...
ORGANISM(S): Rattus norvegicus 
2014-08-02 | E-GEOD-60013 | biostudies-arrayexpress
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