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GenomicsFlavobacterium sp. NG2 isolate:The West coast area
Flavobacterium sp. NG2 isolate:The West coast area Genome sequencing
PRJNA1043879 | ENA
ProteomicsNG2 is a target gene of MLL-AF4 that underlies glucocorticoid resistance in infant MLL-rearranged B-ALL by regulating NR3C1 expression through interaction with FLT3
B-cell acute lymphoblastic leukemia (B-ALL) is the most common pediatric cancer, with long-term overall survival rates of 80%. However, B-ALL harboring rearrangements of the MLL gene (also known as KTM2A), hereinafter termed MLLr B-ALL, is frequently seen in infants and is associated with poor 5-yea...
ORGANISM(S): Homo sapiens (Human) 
2024-07-12 | PXD041875 | Pride
Nr3c1 Ap-1 Mll-af4 Flt3 Infant b-all Glucocorticoid resistance Ng2 
GenomicsNG2/CSPG4 regulates cartilage degeneration during TMJ osteoarthritis
NG2/CSPG4 regulates cartilage degeneration during TMJ osteoarthritis
PRJNA883722 | ENA
TranscriptomicsSingle cell expression profiling of NG2 cell lineage from adult mice cortex three days after focal cerebral ischemia
Ischemic stroke is a serious medical condition that leads to neurological symptoms such as loss of motor and cognitive function. Focal cerebral ischemia (FCI) occurs due to interruption of blood supply to the site of injury, leading to the death of brain cells. Cells carrying Neural-glial antigen 2 ...
ORGANISM(S): Mus musculus 
2023-09-21 | E-MTAB-11967 | biostudies-arrayexpress
TranscriptomicsSingle cell expression profiling of NG2 cell lineage upon inhibition of Wnt signaling in adult mice cortex three days after focal celebral ischemia
Ischemic stroke is a severe medical condition that leads to neurological impairments, including the loss of sensory, motor, and cognitive functions. Focal cerebral ischemia (FCI) occurs when blood supply to a specific brain region is interrupted, resulting in cell death. Cells expressing neural-glia...
ORGANISM(S): Mus musculus 
2026-08-05 | E-MTAB-14905 | biostudies-arrayexpress
TranscriptomicsSingle cell expression profiling of NG2 cell lineage upon constitutive activation of Wnt/β-catenin signaling in adult mice cortex three days after focal celebral ischemia
Ischemic stroke is a severe medical condition that leads to neurological impairments, including the loss of sensory, motor, and cognitive functions. Focal cerebral ischemia (FCI) occurs when blood supply to a specific brain region is interrupted, resulting in cell death. Cells expressing neural-glia...
ORGANISM(S): Mus musculus 
2026-08-05 | E-MTAB-14958 | biostudies-arrayexpress
TranscriptomicsRNA-seq of brain mural cells and microvascular fragments
Purpose: Pericytes, the mural cells of blood microvessels, have come into focus as regulators of microvascular development and function, but due to paucity of defining markers, the identification and functional characterization of PC remain problematic, and reported data are often controversial. Her...
ORGANISM(S): Mus musculus 
2016-10-24 | E-GEOD-75668 | biostudies-arrayexpress
TranscriptomicsGene Expression Profile of high grade glioma in Nestin-creERT2 and NG2-creERTM driven tumor suppressors knockout mouse model
Mouse model with P53f/f;Nf1f/+;Ptenf/+ configuration driven by Nestin-creERT2 and NG2-creERTM induced at 1 month postnatal forms high grade glioma in the brain. Tumors were harvested and total RNA were extracted for gene expression profile. Three tumors were harvested from the Nestin-creERT2 mouse m...
ORGANISM(S): Mus musculus 
2015-07-30 | E-GEOD-57038 | biostudies-arrayexpress
TranscriptomicsThe role of Ng2/Cspg4 in soft tissues sarcoma
NG2/CSPG4 is expressed in soft tissue sarcomas, however, its function in this tumor type, and its capacity to serve as a therapeutic target are unknown. Here, we used genetically engineered mice and cells from human tumors to determine the function of Ng2/Cspg4 in soft tissue sarcoma initiation and ...
ORGANISM(S): Mus musculus 
2017-04-07 | GSE97489 | GEO
TranscriptomicsNG2/CSPG4 regulates cartilage degeneration during TMJ osteoarthritis
Changes in the mechanical homeostasis of the temporomandibular joint (TMJ) can lead to the initiation and progression of degenerative arthropathies such as osteoarthritis (OA). Cells sense and engage with their mechanical microenvironment through interactions with the extracellular matrix. In the ma...
ORGANISM(S): Mus musculus 
2022-09-24 | GSE214077 | GEO
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