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UnknownAnti-microbial activity of whole blood and plasma collected from Anna's Hummingbirds (Calypte anna) against three different microbes.
Not available
S-EPMC7289396 | biostudies-literature
ProteomicsRetina-Targeted 17β-Estradiol by the DHED Prodrug Rescues Visual Function and Actuates Neuroprotective Protein Net-works after Optic Nerve Crush in a Rat Model of Surgical Menopause. Katalin Prokai-Tatrai, Khadiza Zaman, Ammar Kapic, Kelleigh Hogan , Gabriela Sanchez-Rodriguez, Anna E. Silverio Vien Nguyen , Laszlo Prokai and Andrew J. Feola
The association between 17β-estradiol (E2) deprivation, seen in menopause and a risk for devel-oping glaucoma, has been shown. Thus, exogenous supplementation of E2 may protect against retinal ganglion cell (RGC) degradation and vision loss. Here, we investigated the utility of topical 10β,17β-dihyd...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-07 | PXD059520 | Pride
Bioinformatics  dhed  estrogen  glaucoma  menopause  optic nerve crush  optomotor response  protein–protein interaction networks  quantitative label-free retina proteomics 
UnknownPredictors of aromatase inhibitor discontinuation as a result of treatment-emergent symptoms in early-stage breast cancer.
Not available
S-EPMC3341106 | biostudies-literature
ProteomicsMolecular Basis of the mechanisms controlling MASTL - Proteomics analysis of MASTL substrate proteome and phosphorylation state
As part of our study on human MASTL (microtubule-associated serine/threonine kinase-like), we used mass spectrometry (MS)-based proteomics in the aim to unravel novel aspects about MASTL activation, regulation and potential substrates. Specifically, we performed a phosphoproteomics-based kinase assa...
ORGANISM(S): Homo sapiens (Human) 
2020-01-09 | PXD007991 | Pride
Human Lc-msms Mastl 
TranscriptomicsGene expression profiling upon knockdown of JAK1 in IM9 cells
Natural Killer (NK) cells are primary effectors of innate immunity directed against transformed cells. In response, tumor cells have developed mechanisms to evade NK cell-mediated lysis but the molecular basis for target cell resistance is not well understood. In the present study, we used a lentivi...
ORGANISM(S): Homo sapiens 
2012-06-27 | E-GEOD-37012 | biostudies-arrayexpress
UnknownTargeting CXCR4 abrogates resistance to trastuzumab by blocking cell cycle progression and synergizes with docetaxel in breast cancer treatment.
Not available
S-EPMC10245436 | biostudies-literature
GenomicsVariants from a subset of genes from WES of adult AML patient samples
The aim if this study was to identify variants in a specific list of genes in samples from adult AML patients. The gene list includes DNA repair and mitochondrial respiratory chain genes.
EGAS00001006185 | EGA
UnknownSignaling lymphocytic activation molecules Slam and cancers: friends or foes?
Not available
S-EPMC5882332 | biostudies-literature
UnknownFull eradication of pre-clinical human papilloma virus-induced tumors by a lentiviral vaccine.
Not available
S-EPMC10565635 | biostudies-literature
TranscriptomicsTranscription profiling of human and mouse keratinocytes infected with AD and Ad-NotchIC viruses reveals cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
Notch signaling promotes commitment of keratinocytes to differentiation and suppresses tumorigenesis. p63, a p53 family member, has been implicated in establishment of the keratinocyte cell fate and/or maintenance of epithelial self-renewal. Here we show that p63 expression is suppressed by Notch1 a...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5229 | biostudies-arrayexpress
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