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TranscriptomicsTranscription profiling of genetically cerebral malaria-resistant (CM-R) and cerebral malaria-susceptible (CM-S) mouse strains
Gene expression patterns were investigated in well-defined genetically cerebral malaria-resistant (CM-R) and cerebral malaria-susceptible (CM-S) mouse strains. cDNA microarrays were used to search for differentially expressed genes in mouse brain. Four mouse strains, known to differ in susceptibilit...
ORGANISM(S): Mus musculus 
2005-06-30 | E-MEXP-370 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of CD8+ T cells from BM3.3 transgenic mice during responses to TCR ligands of different avidity
To identify the molecular bases for divergence in differentiation programs of naïve CD8 T cells, we monitored gene expression profile of CD8+ T cells from BM3.3 transgenic mice during responses to TCR ligands of different avidity (full response with antigen presenting cells from C57BL/6 mice , parti...
ORGANISM(S): Mus musculus 
2004-07-07 | E-MEXP-16 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles of PBMC Characterize Inflammation Stages in the Acute Lung Injury in Mice
Acute respiratory distress syndrome (ARDS) carries about a 50 percent mortality and is frequently associated with an infection (sepsis). Life-support treatment with mechanical ventilation rescues many patients, although superimposed infection or multiple organ failure can result in death. The outcom...
ORGANISM(S): Mus musculus 
2011-06-01 | E-GEOD-19030 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of thymocyte differentiation in knockout mouse models
Microarray experiment with whole thymi from genetically enginereed mice, with purified thymocyte samples and with cell lines.
ORGANISM(S): Mus musculus 
2004-06-30 | E-MEXP-96 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of CD8+CD57+ T cells from healthy donors and HIV patients
Gene Array Analysis of CD8+ CD57+ T cells in HIV Patients. Gene expression patterns of CD8+CD57+ T cells from healthy donors and HIV patients were compared. Gene expression patterns of CD8+CD57- T cells and CD8+CD57+ T cells were compared.
ORGANISM(S): Homo sapiens 
2005-07-30 | E-MEXP-393 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of brain tissue from cerebral malaria-resistant and susceptible strains of mice in a time series following infection with Plasmodium berghei
Microarray analyses allow the identification and assessment of molecular signatures in whole tissues undergoing pathological processes. To better understand cerebral malaria pathogenesis, we investigated intra-cerebral gene-expression profiles in well-defined genetically cerebral malaria-resistant (...
ORGANISM(S): Mus musculus 
2007-05-01 | E-MEXP-1018 | biostudies-arrayexpress
ProteomicsRetina-Targeted 17β-Estradiol by the DHED Prodrug Rescues Visual Function and Actuates Neuroprotective Protein Net-works after Optic Nerve Crush in a Rat Model of Surgical Menopause. Katalin Prokai-Tatrai, Khadiza Zaman, Ammar Kapic, Kelleigh Hogan , Gabriela Sanchez-Rodriguez, Anna E. Silverio Vien Nguyen , Laszlo Prokai and Andrew J. Feola
The association between 17β-estradiol (E2) deprivation, seen in menopause and a risk for devel-oping glaucoma, has been shown. Thus, exogenous supplementation of E2 may protect against retinal ganglion cell (RGC) degradation and vision loss. Here, we investigated the utility of topical 10β,17β-dihyd...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-07 | PXD059520 | Pride
Bioinformatics  dhed  estrogen  glaucoma  menopause  optic nerve crush  optomotor response  protein–protein interaction networks  quantitative label-free retina proteomics 
TranscriptomicsGene expression analysis of the antiviral effect of chloroquine and derivatives on in vitro HCV infected cells.
The main goal of this study is to characterize the transcriptional modulations induced by antiviral compounds derived from chloroquine on Huh7 cells infected with HCV. And thus to identify among the genes modulated by infection, those who are regulated by chloroquine and potentially involved in the ...
ORGANISM(S): Homo sapiens 
2012-06-30 | E-GEOD-30351 | biostudies-arrayexpress
UnknownUbiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter.
Not available
S-EPMC2698723 | biostudies-literature
TranscriptomicsHigh resolution analysis of genomic imprinting in the embryonic and adult mouse brain AND Sex-specific imprinting in the mouse brain
Genomic imprinting results in the preferential expression of the paternal, or maternal allele of certain genes. We have performed a genome-wide characterization of imprinting in the mouse embryonic and adult brain using F1 hybrid mice generated from reciprocal crosses of CASTEiJ and C57BL/6J mice. ...
ORGANISM(S): Mus musculus 
2010-07-08 | E-GEOD-22131 | biostudies-arrayexpress
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