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UnknownRandomized phase III trial to test accelerated versus standard fractionation in combination with concurrent cisplatin for head and neck carcinomas in the Radiation Therapy Oncology Group 0129 trial: long-term report of efficacy and toxicity.
Not available
S-EPMC4239304 | biostudies-literature
TranscriptomicsExpression analysis in mouse female PGK12.1 ES cells by RNA-seq
Many animal species employ a chromosome-based mechanism of sex determination, which has led to coordinate evolution of dosage compensation systems. Dosage compensation not only corrects the imbalance in the number of X-chromosomes between the sexes, but is also hypothesized to correct dosage imbalan...
ORGANISM(S): Mus musculus 
2011-07-19 | E-GEOD-30690 | biostudies-arrayexpress
UnknownAnalyse des Hautmikrobioms eines an junktionaler Epidermolysis bullosa erkrankten Patienten nach Behandlung mit genetisch modifizierten Stammzellen
Not available
S-EPMC12435134 | biostudies-literature
TranscriptomicsDichlorvos exposure results in large scale disruption of energy metabolism in the liver of the zebrafish, Danio rerio
Background: Exposure to dichlorvos (DDVP), an organophosphorus pesticide, is known to result in neurotoxicity as well as other metabolic perturbations. However, the molecular causes of DDVP toxicity are poorly understood, especially in cells other than neurons and muscle cells. To obtain a better un...
ORGANISM(S): Danio rerio 
2015-11-05 | E-GEOD-66257 | biostudies-arrayexpress
ProteomicsProximity labeling proteomics reveals Kv1.3 potassium channel immune interactors in microglia.
Microglia are resident immune cells of the brain and regulate its inflammatory state. In neurodegenerative diseases, microglia transition from a homeostatic state to a state referred to as disease associated microglia (DAM). DAM express higher levels of proinflammatory signaling molecules, like STAT...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2024-05-06 | PXD049433 | Pride
Proximity labeling Neurodegeneration Neuroinflammation Kv1.3 potassium channel Microglia 
UnknownE. coli 70S ribosome with unmodified lys-tRNAPro(GGG) bound to slippery P-site CCC-C codon
Not available
EMPIAR-13308 | biostudies-other
TranscriptomicsTranscription profiling of mouse liver from JNK knocked down animals
Liver-specific Knockdown of JNK1 Up-regulates Proliferator-activated Receptor Coactivator 1 and Increases Plasma Triglyceride despite Reduced Glucose and Insulin Levels in Diet-induced Obese Mice. The c-Jun N-terminal kinases (JNKs) have been implicated in the development of insulin resistance, dia...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7648 | biostudies-arrayexpress
TranscriptomicsExpression data from human triploid and diploid fibroblast cell cultures
Dosage compensation restores a balanced network of gene expression between autosomes and sex chromosomes in males (XY) and females (XX). In mammals, this is achieved by doubling the expression of X-linked genes in both sexes, together with X inactivation in females. X up-regulation may be controlled...
ORGANISM(S): Homo sapiens 
2009-11-06 | E-GEOD-18877 | biostudies-arrayexpress
MetabolomicsMetabolomic signatures discriminate horses with clinical signs of atypical myopathy from healthy co-grazing horses
Atypical myopathy (AM) is a severe rhabdomyolysis syndrome that occurs in grazing horses. Despite the presence of toxins in their blood, all horses from the same pasture are not prone to display clinical signs of AM. The objective of this study was to compare the blood metabolomic profiles of horses...
2021-08-31 | MTBLS2579 | MetaboLights
UnknownE. coli 70S ribosome with unmodified tRNAPro(GGG) bound to slippery P-site CCC-C codon and tRNAVal(UAC) in the A site
Not available
EMPIAR-13309 | biostudies-other
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