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ProteomicsCD70 Regulates the NF1/Ras/ERK Axis to Promote Metastatic Potential in Clear Cell Renal Cell Carcinoma
This study is the first report demonstrating a novel mechanism by which CD70 promotes clear cell renal cell carcinoma (ccRCC) progression and metastasis, at least in part, through suppression of NF1 and subsequent activation of the Ras/ERK signaling pathway, which may further drive EMT-related featu...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD069813 | Pride
Emt Cd70 Nf1 Combination therapy Ras/erk pathway Proteomics Metastasis Ccrcc 
UnknownShen-Bai-Jie-Du decoction suppresses the progression of colorectal adenoma to carcinoma through regulating gut microbiota and short-chain fatty acids.
Not available
S-EPMC11514841 | biostudies-literature
UnknownEvaluation of new robust silk fibroin hydrogels for posterior scleral reinforcement in rabbits.
Not available
S-EPMC10300450 | biostudies-literature
UnknownMachine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Not available
S-EPMC12802299 | biostudies-literature
GenomicsChromatin modification by SUMO-1 stimulates the promoters of translation machinery genes
We determined the occupancy of SUMO-1 on chromatin in HeLa cells by use of chromatin affinity purification coupled with next generation sequencing 18 samples examined in syncrhonized HeLa cells: Cells in G1, early S (S0)/mid (S3)/ late S phase (S6), and mitosis (M), triplicates for each sample. 1 Ch...
ORGANISM(S): Homo sapiens 
2012-10-02 | E-GEOD-41264 | biostudies-arrayexpress
UnknownEffects of ferulic acid esterase-producing Lactobacillus fermentum and cellulase additives on the fermentation quality and microbial community of alfalfa silage.
Not available
S-EPMC6788448 | biostudies-literature
UnknownHigh extracellular matrix stiffness upregulates TNNT1 to awaken dormant tumor cells in liver metastatic niches of gastric cancer.
Not available
S-EPMC12119719 | biostudies-literature
UnknownAn 8‑gene signature predicts the prognosis of cervical cancer following radiotherapy.
Not available
S-EPMC6755236 | biostudies-literature
UnknownNAT10-mediated ac4C modification of KDM1B drives osteoarthritis progression through epigenetic suppression of SOX9.
Not available
S-EPMC12647510 | biostudies-literature
GenomicsGenome-wide maps of Yan chromatin association
High-resolution genome-wide binding of Yan used to confirm the presence of high-density regions seen in ChIP-chip ChIP-Seq of Yan protein in stage 11 Drosophila embryos
ORGANISM(S): Drosophila melanogaster 
2013-03-01 | E-GEOD-34040 | biostudies-arrayexpress
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