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ProteomicsCD70 Regulates the NF1/Ras/ERK Axis to Promote Metastatic Potential in Clear Cell Renal Cell Carcinoma
This study is the first report demonstrating a novel mechanism by which CD70 promotes clear cell renal cell carcinoma (ccRCC) progression and metastasis, at least in part, through suppression of NF1 and subsequent activation of the Ras/ERK signaling pathway, which may further drive EMT-related featu...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD069813 | Pride
Emt Cd70 Nf1 Combination therapy Ras/erk pathway Proteomics Metastasis Ccrcc 
ProteomicsStable Coordination Unlocks Ligand-accelerated Transition Metal Catalysis on Proteins
This project investigates in situ deprotection reactions catalyzed by the Ni–BCS system in MC38 cells and the subsequent impact on the immunopeptidome. Two independent MC38 cell preparations (2 × 10⁷ cells each) were pulsed with either the P2 peptide or P2 peptide followed by Ni–BCS catalyzed in sit...
ORGANISM(S): Mus Musculus 
PXD067964 |
UnknownShen-Bai-Jie-Du decoction suppresses the progression of colorectal adenoma to carcinoma through regulating gut microbiota and short-chain fatty acids.
Not available
S-EPMC11514841 | biostudies-literature
UnknownEvaluation of new robust silk fibroin hydrogels for posterior scleral reinforcement in rabbits.
Not available
S-EPMC10300450 | biostudies-literature
UnknownMachine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Not available
S-EPMC12802299 | biostudies-literature
GenomicsChromatin modification by SUMO-1 stimulates the promoters of translation machinery genes
We determined the occupancy of SUMO-1 on chromatin in HeLa cells by use of chromatin affinity purification coupled with next generation sequencing 18 samples examined in syncrhonized HeLa cells: Cells in G1, early S (S0)/mid (S3)/ late S phase (S6), and mitosis (M), triplicates for each sample. 1 Ch...
ORGANISM(S): Homo sapiens 
2012-10-02 | E-GEOD-41264 | biostudies-arrayexpress
UnknownEffects of ferulic acid esterase-producing Lactobacillus fermentum and cellulase additives on the fermentation quality and microbial community of alfalfa silage.
Not available
S-EPMC6788448 | biostudies-literature
ProteomicsA Novel Classifier Based on Urinary Proteomics for Distinguishing between Benign and Malignant Ovarian Tumors
Preoperative differentiation of benign and malignant tumor types is critical for providing individualized treatment interventions to improve prognosis of patients with ovarian cancer. High-throughput proteomics analysis of urine samples was performed to identify reliable and non-invasive biomarkers ...
ORGANISM(S): Homo Sapiens 
PXD027695 |
UnknownHigh extracellular matrix stiffness upregulates TNNT1 to awaken dormant tumor cells in liver metastatic niches of gastric cancer.
Not available
S-EPMC12119719 | biostudies-literature
UnknownAn 8‑gene signature predicts the prognosis of cervical cancer following radiotherapy.
Not available
S-EPMC6755236 | biostudies-literature
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