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MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
ProteomicsTNFα conditional knockout promotes myoblasts proliferation, differentiation and muscle regeneration
TNFα is a cytokine with multiple biological effects. It activates cascading signal pathways by binding to receptors on the cell membrane, regulating processes such as cell growth, differentiation, apoptosis, and inflammatory responses. The formation of skeletal muscle primarily relies on processes s...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-09 | PXD046525 | Pride
Nucleus-cytoplasmic protein separation Tnfα Myogenesis Muscle-specific knockout 
MetabolomicsBacteroides uniformis degrades β-glucan to promote Lactobacillus johnsonii improving indole-3-lactic acid levels in alleviating colitis

The gut microbiota plays a crucial role in the onset and progression of inflammatory bowel disease (IBD). β-glucan (BG), a soluble dietary fiber widely present in oats, barley, fungi, yeast and some bacteria, has multiple bioactive properties such as mitigating intestinal inflammation; however, t...

2024-02-12 | MTBLS8950 | MetaboLights
ProteomicsSite mapping of PGK1 O-GlcNAcylation
To identify the site(s) of O-GlcNAcylation on PGK1, we transiently co-expressed Flag-tagged PGK1 and OGT in HEK293T cells. After immunoprecipitation using anti-Flag M2 beads and in-gel trypsin digestion, resulted peptides were subjected to mass spectrometry analysis
ORGANISM(S): Homo sapiens (Human) 
2019-11-06 | PXD015659 | Pride
Pgk1 
ProteomicsLC-MS/MS detection of proteins involved in Escherichia coli biomineralized nanoparticles
Biomineralization is a naturally occurred process, by which microorganism reduced mental ions to minerals. Bacteria-driven biomineralization is most applied in metal recycling or environmental governance, the biomineralized products are rarely used. This probably due to the attachments of microorgan...
ORGANISM(S): Escherichia coli 
2023-08-25 | PXD044359 | Pride
Biomineralization Escherichia coli Nanoparticle 
UnknownAssociation between apnea-hypopnea index and coronary artery calcification: a systematic review and meta-analysis.
Not available
S-EPMC7877988 | biostudies-literature
UnknownIntegrative analysis of miRNA and mRNA profiles reveals that gga-miR-106-5p inhibits adipogenesis by targeting the KLF15 gene in chickens.
Not available
S-EPMC9258119 | biostudies-literature
UnknownTranscriptome analysis reveals key genes involved in the resistance to Cryphonectria parasitica during early disease development in Chinese chestnut.
Not available
S-EPMC9901152 | biostudies-literature
UnknownComorbid obstructive sleep apnea is associated with adverse cardiovascular outcomes in female patients with acute coronary syndrome complicating metabolic syndrome.
Not available
S-EPMC10270259 | biostudies-literature
UnknownBacillus subtilis BS-15 Effectively Improves Plantaricin Production and the Regulatory Biosynthesis in Lactiplantibacillus plantarum RX-8.
Not available
S-EPMC8837263 | biostudies-literature
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